连南瑶族县妇女孕中期甲状腺功能水平筛查

发布时间：2018-07-03 13:09

本文选题：瑶族 + 甲状腺功能　；参考：《广东医学》2015年11期

【摘要】：目的评估连南瑶族县汉、瑶族妇女妊娠中期甲状腺功能水平,分析民族及地区差异性。方法选择孕13~28周连南地区汉、瑶族妊娠中期妇女110例,测量FT4、TSH、TPOAb水平,并与广州地区100例汉族妊中期妇女比较,探讨不同民族及地区甲状腺功能水平及其差异。结果广州地区孕中期妇女FT4水平较连南地区低(P0.05),但其差异与民族无关;连南地区妊娠中期妇女TSH水平与广州地区差异无统计学意义(P0.05);连南地区汉族、连南地区瑶族、广州地区汉族妊娠期妇女妊娠中期亚甲减发生率分别为3.5%、1.9%、2%,亚甲亢发生率为5.3%、3.8%、2%,甲减发生率为0%、0%、1%,甲亢发生率为0%、3.8%、1%,低甲状腺素血症发生率为5.3%、3.8%、10%,TPOAb阳性率为10.5%、3.8%、8%,但其差异均无统计学意义(P0.05);TPOAb阳性组较阴性组甲功异常发生率明显增高(P0.05)。结论连南地区汉、瑶族妇女甲状腺功能无民族差异,但FT4水平与广州存在地区差异;TPOAb阳性者,甲状腺功能异常发生率明显升高,因此有必要对妊娠期妇女筛查TPOAb。
[Abstract]:Objective to evaluate the thyroid function of Han and Yao women in Liannan Yao county and analyze the difference between different nationalities and regions. Methods 110 cases of Han and Yao women in Liannan district were selected for 1328 weeks of gestation. The levels of TPOAb of FT4TSHSH-TPOAb were measured and compared with 100 women of Han nationality in Guangzhou area. The thyroid function and its difference in different nationalities and regions were studied. Results the level of FT4 in women of second trimester of pregnancy in Guangzhou was lower than that in Liannan (P0.05), but the difference was not related to nationality; there was no significant difference in TSH level between women in second trimester of pregnancy in Liannan and Guangzhou (P0.05); in the Han nationality of Liannan, Yao in Liannan, there was no significant difference between them (P0.05). The incidence of hypothyroidism in the second trimester of pregnancy in the Han nationality in Guangzhou area was 3.51.9. the incidence of hyperthyroidism was 5.3and 3.80.The incidence of hypothyroidism was 0.33 and 3.80.The incidence of hypothyroidism was 0.33.81.The incidence of hypothyroidism was 5.33.81010TPOAb, but there was no difference between the two groups. Statistical significance (P0.05) TPOAb positive group was significantly higher than the negative group A abnormal incidence (P0.05). Conclusion there is no ethnic difference in thyroid function between Han and Yao women in Liannan area, but the incidence of thyroid dysfunction is significantly higher in those with positive FT4 levels than those in Guangzhou. Therefore, it is necessary to screen TPOAbs for pregnant women.
【作者单位】：广东药学院附属第一医院内分泌科;广东药学院附属第一医院核医学科;
【基金】：2013年广东省人口计生委科研课题(编号:20133094)
【分类号】：R714.256

【参考文献】