宫颈微偏腺癌的诊疗现状

发布时间：2018-07-05 09:28

本文选题：宫颈微偏腺癌 + 临床症状　；参考：《河北医科大学》2017年硕士论文

【摘要】：宫颈微偏腺癌(Minimal deviation adenocarcinoma of the uterine cervix,MDA)是一种罕见的高分化粘液腺癌。最主要的临床症状为阴道水样或粘液性排液。常见的临床体征为宫颈肥大或增厚。细胞学检查和宫颈浅表部位活检检出率低。组织病理学方法是MDA确诊的金标准。对于高度怀疑MDA的患者,经反复宫颈细胞学或活检阴性者,应行宫颈深部活检或宫颈锥切术并联合免疫与特殊肿瘤标志物方法进一步明确诊断。MDA的治疗规范与同期别的宫颈腺癌相同。手术仍是早期病变患者的主要治疗手段。放疗和/或化疗建议用于晚期患者。MDA早期便发生转移,预后差,5年生存率不足5%。
[Abstract]:Minimal deviation adenocarcinoma of the uterine cervix carcinoma is a rare highly differentiated mucinous adenocarcinoma. The main clinical symptoms are vaginal water or mucous drainage. Common clinical signs are cervical hypertrophy or thickening. The detection rate of cytological examination and cervical superficial biopsy was low. Histopathology is the gold standard for the diagnosis of MDA. For highly suspected MDA patients, those with recurrent cervical cytology or biopsy negative, Deep cervical biopsy or cervix conization combined with immunoassay and special tumor marker methods should be performed to further clarify the criteria for the diagnosis of. MDA and other cervical adenocarcinoma in the same period. Surgery is still the main treatment for patients with early lesions. Radiotherapy and / or chemotherapy are recommended for advanced patients with early metastasis of MDA, poor prognosis, and 5-year survival rate of less than 5%.
【学位授予单位】：河北医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R737.33

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