青春期女性月经失调与卵巢形态学分析

发布时间：2018-07-14 16:06

【摘要】：目的研究青春期女性月经失调与卵巢形态学的关系,为青春期多囊卵巢综合征(PCOS)的诊断提供参考。方法收集2014年9月至2015年9月于西安交通大学第一附属医院妇科门诊和妇女保健门诊就诊的、初潮2年后青春期月经失调212例患者的临床资料并进行分析。结果212例月经失调患者中,以月经稀发最为常见(33.96%),其次为闭经(16.51%);不同类型月经失调患者F-G评分及痤疮评分差异均有统计学意义(F值分别为1.39、1.77,P均0.05),以月经稀发患者的评分最高;月经稀发患者卵巢体积、窦状卵泡数目、卵巢最大面积均显著高于非月经稀发组(t值分别为2.89、5.76、6.23,P均0.05);正常卵巢组、多滤泡卵巢组、多囊卵巢组的临床表现差异有统计学意义(χ~2=43.25,P0.05);多囊卵巢组月经稀发的发病率最高(49.30%),其次为多滤泡卵巢组(42.59%);血黄体生成素(LH)、睾酮(T)、LH/血清卵泡刺激素(LH/FSH)差异均有统计学意义(F值分别为3.45、2.43、2.76,P均0.05),且多囊卵巢组均为最高;3组中诊断为青春期PCOS的病例数差异有统计学意义(χ~2=26.58,P0.05),同样多囊卵巢组最高,但多滤泡卵巢组也有12例确诊为青春期PCOS(22.22%);212例青春期月经失调患者中共诊断青春期PCOS者45例(21.23%),根据患者体质量指数(BMI)分为肥胖组和非肥胖组,肥胖患者卵巢体积、窦状卵泡数目、卵巢最大面积均显著高于非肥胖者(t值分别为3.42、7.89、4.02,P均0.05),且空腹和2h稳态模型胰岛素抵抗指数(HOMA IR)均显著升高(t值分别为8.89、10.62,P均0.05)。结论月经稀发是青春期月经失调最为常见的类型,月经稀发及肥胖患者多数伴卵巢形态学异常,应定期随访。
[Abstract]:Objective to study the relationship between menstrual disorders and ovarian morphology in puberty women, and to provide a reference for the diagnosis of puberty polycystic ovary syndrome (PCOS). Methods from September 2014 to September 2015, 212 patients in the First Affiliated Hospital of Xi'an Jiao Tong University gynecologic outpatient department and women health clinic were treated, and 212 cases of adolescent menstrual disorder after 2 years of menarche were given. Results of the 212 patients with menstrual disorders, the most common menorrhagia (33.96%) and the second were amenorrhea (16.51%). The difference of F-G score and acne score in different types of menstrual disorders were statistically significant (F value was 1.39,1.77, P was 0.05), and the patients with dilute menstruation were the highest. The number of sinus like follicles and the largest area of the ovary were significantly higher than those in the non menorrhea group (t value was 2.89,5.76,6.23, P was 0.05 respectively), and the clinical manifestations of the normal ovary group, the polyfollicle ovary group and the polycystic ovary group were statistically significant (x ~2=43.25, P0.05), and the incidence of dilute menstruation in the polycystic ovum nest group was the highest (49.30%), followed by the polyfollicle ovary. Group (42.59%); serum luteinizing hormone (LH), testosterone (T), LH/ serum follicle stimulating hormone (LH/FSH) differences were statistically significant (F value was 3.45,2.43,2.76, P 0.05), and polycystic ovary group were the highest; the number of cases diagnosed as puberty PCOS in the 3 groups was statistically significant (x ~2=26.58, P0.05), the same polycystic ovarian group was the highest, but multiple follicles. The ovarian group also had 12 cases of puberty PCOS (22.22%); 212 cases of adolescent menstrual disorders were diagnosed as PCOS in 45 cases (21.23%). According to the body mass index (BMI), the volume of the ovary, the number of sinus like follicles and the maximum area of the ovary were significantly higher than those of the non obese patients (t value was 3.42,7., respectively, respectively). 89,4.02, P were 0.05), and the insulin resistance index (HOMA IR) of the fasting and 2H steady-state models increased significantly (t value was 8.89,10.62, P was 0.05 respectively). Conclusion menstrual dilute hair is the most common type of menstrual disorder in puberty. Most patients with menstrual dilute and obese patients with ovarian morphologic abnormalities should be regularly followed up.
【作者单位】：西安交通大学第一附属医院妇产科;
【分类号】：R711.51

【相似文献】