孕妇血栓弹力图正常值参考范围的建立

发布时间：2018-07-14 16:18

【摘要】：目的建立评价孕妇凝血功能血栓弹力图(TEG)正常值参考范围。方法按照怀孕与否与体检结果将166名孕妇和64名未孕健康妇女分别纳入怀孕组和非怀孕(对照)组,检测其TEG值、传统凝血指标值;分析比较2组妇女TEG各参数,对存在差异的参数建立参考值范围。进一步分析足月妊娠对TEG结果的影响;对孕妇传统凝血指标与TEG检测结果做相关性分析。结果孕妇和健康未孕妇女的传统凝血指标和TEG检测结果存在明显不同,根据结果建立的新的TEG参考范围:R 3.9-7.5 min,K 1.0-2.4 min,α57.6°-74.9°,MA 55.7-75.7 mm,LY30 0-0.56%,CI(-0.97)-3.6。足月妊娠对TEG结果无明显影响。除LY30外,孕妇TEG其他参数均与传统凝血指标具有一定的相关性。结论一般人群的TEG参考值范围不适用于孕妇;建立起的孕妇TEG正常值参考范围可应用于临床。
[Abstract]:Objective to establish a reference range for evaluating the normal value of thromboelastography (TEG) in pregnant women. Methods 166 pregnant women and 64 non-pregnant healthy women were divided into pregnancy group and non-pregnant (control) group according to the results of pregnancy and physical examination, the TEG value and the traditional coagulation index value were measured, and the parameters of TEG were analyzed and compared between the two groups. Establish a range of reference values for different parameters. The effect of term pregnancy on the results of TEG was further analyzed, and the correlation between the traditional coagulation parameters and the results of TEG was analyzed. Results there were significant differences between the traditional coagulation indexes and the test results of TEG in pregnant women and healthy non-pregnant women. According to the results, a new reference range of TEG: 1: R 3.9-7.5 min K 1.0-2.4 min, 伪 57.6 掳-74.9 掳MA 55.7-75.7 mm LY30 0-0.56 CI (-0.97) -3.6 was established. Term pregnancy had no significant effect on the outcome of TEG. With the exception of LY30, the other parameters of TEG in pregnant women were correlated with the traditional coagulation parameters. Conclusion the reference range of TEG in general population is not suitable for pregnant women, and the normal reference range of TEG for pregnant women can be used in clinic.
【作者单位】：中南大学湘雅三医院输血科;
【基金】：中南大学研究生自主探索创新项目(2017zzts835)
【分类号】：R714.1

【相似文献】