阿托西班与利托君治疗高龄孕妇先兆早产临床观察

发布时间：2018-07-17 01:45

【摘要】：目的观察阿托西班与利托君治疗高龄孕妇先兆早产的效果及围生儿结局。方法接受保胎治疗的先兆早产孕妇199例,根据孕妇年龄及应用的保胎药物不同分为高龄(年龄≥35岁)阿托西班组(A组)47例、适龄(20岁年龄35岁)阿托西班组(B组)52例、高龄利托君组(C组)50例、适龄利托君组(D组)50例,比较各组治疗效果效果、不良反应及围生儿结局。结果 1A组48 h有效率、7 d有效率及围生儿结局不及B组,两组相比,P均0.05;A、B组两组不良反应发生率相比,P0.05。2A、C组孕妇不良反应发生率相比,P0.05;但A、C组48 h和7 d有效率、围生儿结局相比,P0.05。3C组48 h和7 d有效率低于D组,其不良反应发生率、新生儿窒息率及围生儿死亡率高于D组,两组相比,P均0.05。结论阿托西班与利托君治疗高龄孕妇先兆早产的保胎效果、围生儿结局相近,但两种药物对高龄孕妇先兆早产的保胎效果、围产儿结局均差于适龄孕妇先兆早产,高龄孕妇应用阿托西班的安全性好于利托君。
[Abstract]:Objective to observe the effect and perinatal outcome of atoxiban and litojun in the treatment of threatened premature delivery of elderly pregnant women. Methods 199 pregnant women with threatened preterm delivery who received fetal preservation therapy were divided into four groups according to the age of the pregnant women and the antifetal drugs used. According to the age of the pregnant women, 47 cases were in the atossiban group (age 鈮，

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