衣原体属及支原体属阳性与宫颈糜烂相关性研究

发布时间：2018-07-20 21:35

【摘要】：目的探讨衣原体属及支原体属阳性与宫颈糜烂存在的相关性,并研究不同程度宫颈糜烂患者感染衣原体属及支原体属的阳性率。方法于2012年12月-2013年12月收治的326例宫颈糜烂患者中,在排除假丝酵母菌阴道炎患者后,按照数学随机选取的方法抽取180例患者作为试验组,根据临床症状以及血样检测判断其患病程度,并以此将患者分为重、中、轻度患者3组,选取180名宫颈健康者作为对照组,分别对宫颈糜烂患者及宫颈健康者进行宫颈分泌物采样,并检测其衣原体属、支原体属阳性率,数据采用SPSS12.0软件进行统计分析。结果试验组病原体阳性率70.56%,明显高于对照组的20.00%,差异有统计学意义(P0.05);试验组20~40岁的性活跃期患者病原体阳性率较高,其中30~39岁年龄段病原体阳性率最高为83.56%,20岁患者2例,50岁患者4例,判定为阳性者分别为2例和1例,但由于样本数量过少,阳性率差异无统计学意义;试验组患者宫颈糜烂程度的不同其病原体阳性率不同,宫颈糜烂程度越深、阳性率越高。结论衣原体属及支原体属阳性与宫颈糜烂关系密切,宫颈糜烂程度的不同其衣原体属及支原体属的阳性率不同,总体表现为宫颈糜烂程度越深,阳性率越高。
[Abstract]:Objective to investigate the relationship between the positive rate of chlamydia and mycoplasma and cervical erosion, and to study the positive rates of chlamydia and mycoplasma in different degree of cervical erosion. Methods from December 2012 to December 2013, in 326 patients with cervical erosion, 180 patients were selected as experimental group according to the method of mathematical random selection after the removal of Candida vaginitis. According to the clinical symptoms and blood samples, the patients were divided into three groups: severe, moderate and mild. 180 healthy cervical patients were selected as control group. Cervical secretion samples were collected from cervical erosion patients and cervical healthy subjects, and the positive rates of chlamydia and mycoplasma were detected. The data were analyzed by SPSS 12.0 software. Results the positive rate of pathogens in the test group was 70.56, which was significantly higher than that in the control group (20.00) (P0.05), and the positive rate of pathogens in the experimental group (2040 years old) was higher than that in the control group (P0.05). Among them, the highest positive rate of pathogens was 83.56 years old and 20 years old, 2 cases were 50 years old, 2 cases were positive, and 1 case was positive. However, there was no significant difference in the positive rate because of the small number of samples. The different degree of cervical erosion in the trial group had different positive rate of pathogen, the deeper the degree of cervical erosion was, the higher the positive rate was. Conclusion the positive rate of Chlamydia and Mycoplasma is closely related to cervical erosion. The positive rate of Chlamydia and Mycoplasma is different with the degree of cervical erosion. The overall manifestation is that the deeper the degree of cervical erosion, the higher the positive rate.
【作者单位】：滨州医学院附属医院生殖医学科;滨州医学院附属医院妇产科;山东大学药学院;
【基金】：国家重点基础研究基金资助项目(2006CB708512)
【分类号】：R711.32

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