B超引导内镜下治疗在妊娠期急性重症胰腺炎早期治疗中的价值

发布时间：2018-07-26 06:51

【摘要】：目的探讨早期B超引导内镜下十二指肠乳头括约肌切开术(EST)和鼻胆管引流(ENBD)术在妊娠期急性重症胰腺炎治疗中的价值。方法将38例妊娠期急性重症胰腺炎患者按随机法分为内镜治疗组13例及对照组25例。内镜治疗组在入院后72 h内行B超引导内镜下EST和ENBD术以及多学科综合治疗,对照组仅行多学科综合治疗。比较两组患者治疗前和治疗7 d后APACHEⅡ(急性生理和慢性健康评价指标Ⅱ)评分、谷草转氨酶、总胆红素和C反应蛋白差异,以及腹痛缓解时间、肠功能恢复时间、30 d内胰腺假性囊肿、胰腺脓肿以及全身并发症发生率和终止妊娠率、住院天数的差异。结果两组治疗前APACHEⅡ评分、谷草转氨酶、总胆红素和C反应蛋白差异无显著性(P0.05),内镜治疗组7 d后APACHEⅡ评分(6.68±1.38)分,谷草转氨酶(128.38±60.93)u/L,总胆红素(44.62±15.59)mmol/L,C反应蛋白(84.08±26.06)mmol/L;腹痛缓解时间(9.57±2.09)d,肠功能恢复时间(12.74±2.52)d。30 d内胰腺假性囊肿、胰腺脓肿和全身并发症发生率分别30.8%、7.7%和21.1%;终止妊娠率69.2%和住院天数(38.32±8.56)d,比较对照组明显下降,差异有显著性(P0.05)。结论妊娠期急性重症胰腺炎患者给予早期72 h以内B超引导内镜下十二指肠乳头括约肌切开术(EST)和鼻胆管引流(ENBD)术安全、可行,治疗效果明显。
[Abstract]:Objective to evaluate the value of early endoscopic sphincterotomy (EST) and nasobiliary drainage (ENBD) in the treatment of severe acute pancreatitis complicating pregnancy. Methods 38 patients with severe acute pancreatitis in pregnancy were randomly divided into endoscopic treatment group (n = 13) and control group (n = 25). The endoscopic treatment group received EST and ENBD under B-ultrasound guidance and multi-disciplinary comprehensive therapy within 72 hours after admission, while the control group only received multi-disciplinary comprehensive therapy. The scores of APACHE 鈪，

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