B族链球菌感染与阴道微生态失调对胎膜早破和妊娠结局的影响研究

发布时间：2018-07-31 15:48

【摘要】：目的探讨B族链球菌感染和阴道微生态失调与胎膜早破的关系及其对妊娠结局的影响。方法选择医院2015年1月-2016年12月足月胎膜早破孕妇80例为胎膜早破组,足月未胎膜早破孕妇80例为对照组;观察两组孕妇下生殖道B族链球菌感染和阴道微生态结果。结果胎膜早破组阴道pH值4.5比例、B族链球菌感染率、微生态失调发生率为58.75%、17.50%、85.00%均高于对照组32.50%、3.75%、55.00%(P0.05),两组阴道清洁度、外阴阴道假丝酵母菌阴道炎、细菌性阴道病比较差异无统计学意义;80例胎膜早破患者中,B族链球菌阳性患者绒毛膜羊膜炎、产褥感染、胎儿窘迫和新生儿肺炎的发生率为35.71%、35.71%、42.86%、28.57%均高于B族链球菌阴性患者6.06%、7.58%、7.58%、4.55%(P0.05);微生态失衡患者和微生态正常患者绒毛膜羊膜炎、产褥感染、胎儿窘迫、新生儿肺炎比较差异无统计学意义。结论足月胎膜早破孕妇B族链球菌感染增加绒毛膜羊膜炎、产褥感染、胎儿窘迫和新生儿肺炎的发生率,阴道微生态失调对妊娠结局影响较小。
[Abstract]:Objective to investigate the relationship between group B streptococcus infection and vaginal microecological disorder and premature rupture of fetal membrane and its effect on pregnancy outcome. Methods from January 2015 to December 2016, 80 pregnant women with premature rupture of membranes were selected as the group of premature rupture of membranes and 80 cases as control group, and the results of B streptococcus infection and vaginal microecology in the lower genital tract of pregnant women were observed. Results the vaginal pH value of premature rupture of membranes group was 4.5, the incidence of microecologic disorder was 58.75 and 17.50%, and 85.00% was higher than that of the control group (P 0.05). The vaginal cleanliness, vulvovaginal candida vaginitis and vaginitis of the two groups were significantly higher than that of the control group (P 0.05). There was no significant difference in bacterial vaginosis. In 80 patients with premature rupture of membranes, chorioamnionitis and puerperal infection were found in group B streptococcus positive patients. The incidence of fetal distress and neonatal pneumonia was 35.71% and 28.57% higher than that of group B streptococcus negative patients (P 0.05), while there was no significant difference between microecological unbalance patients and microecological normal patients with chorioamnionitis, puerperal infection, fetal distress and neonatal pneumonia. Conclusion the incidence of chorioamnionitis, puerperal infection, fetal distress and neonatal pneumonia were increased in pregnant women with premature rupture of membranes.
【作者单位】：台州恩泽医疗中心(集团)浙江省台州医院妇产科;
【分类号】：R714.433

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