宫腔粘连综合治疗218例预后分析

发布时间：2018-08-05 16:43

【摘要】：目的探讨以宫腔镜电切术为主的综合治疗方法对宫腔粘连(intrauterine adhesion,IUA)预后的影响。方法对2010年1月至2013年6月湖北省妇幼保健院因IUA行电切手术的218例患者临床资料进行回顾性分析。各程度IUA根据术后补充雌激素剂量和周期数不同分为3组,A组9 mg/d,服用3周期;B组6 mg/d,服用2周期;C组4 mg/d,服用1周期。观察3周期后月经恢复及宫腔情况并随访妊娠结局。结果宫腔恢复良好86.2%(188/218),月经改善75.7%(165/218);随访8~46个月,受孕44.5%(97/218),活产48.5%(47/97)。Ⅱ度与Ⅲ度IUA的宫腔恢复率、月经改善率差异无统计学意义(P0.05),但二者与Ⅳ度以上IUA的宫腔恢复率、月经改善率差异均有统计学意义(P0.05)。在相同程度IUA中A、B、C 3组比较,宫腔恢复率、月经改善率差异均无统计学意义(P0.05)。结论以宫腔镜电切术为主的综合治疗方法对IUA治疗效果良好;轻、中度IUA预后明显好于重度IUA;适当减少雌激素剂量,缩短治疗周期对IUA预后无明显影响。
[Abstract]:Objective to investigate the effect of hysteroscopic electroresection on the prognosis of intrauterine adhesion IUA. Methods from January 2010 to June 2013, the clinical data of 218 patients undergoing electrosurgical resection of IUA in Hubei Maternal and Child Health Hospital were retrospectively analyzed. According to the dose of estrogen supplementation and the number of cycles, IUA was divided into three groups: group A (9 mg / d), group B (3 cycles), group B (6 mg / d), group C (2 cycles), group C (4 mg / d), and group C (1 cycle). The recovery of menstruation and uterine cavity after 3 cycles were observed and pregnancy outcome was followed up. Results the recovery rate of uterine cavity was 86.2% (1888 / 218), menstrual improvement was 75.7% (165 / 218), follow-up for 8-46 months, conception 44.5% (97 / 218), live birth 48.5% (47 / 97). There was no significant difference in recovery rate between 鈪，

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