息肉样子宫内膜异位症10例临床病理分析

发布时间：2018-08-05 16:46

【摘要】：目的探讨息肉样子宫内膜异位症的病理组织学特征。方法对10例息肉样子宫内膜异位症进行回顾性分析,观察其临床病史、大体及镜下特征以及免疫表型特征。结果 10例患者年龄27~54岁,平均39.4岁,临床症状均表现为盆腔包块,在卵巢、子宫浆膜面及子宫颈管均表现为外生性或息肉样生长,同时并存相应部位的子宫内膜异位症或内膜样囊肿;镜下见病变由良性子宫内膜样腺体和子宫内膜样间质组成,内膜腺体常呈单纯性增生过长,伴输卵管黏膜纤毛细胞化生,间质可发生纤维化,伴不典型间质细胞。随访的9例患者均存活,未见病变复发。结论息肉样子宫内膜异位症在子宫内膜异位症基础上出现局部异位内膜的过度生长,是一种少见的子宫内膜异位症的特殊表现形式,易误诊为腺肉瘤。认识该类病变的最重要意义在于避免术中、术后病理检查中误判为恶性肿瘤或其他良性肿瘤性病变,影响其临床处理和治疗。
[Abstract]:Objective to investigate the histopathological features of polypoid endometriosis. Methods Ten cases of polypoid endometriosis were retrospectively analyzed and their clinical history, gross and microscopic features and immunophenotypic features were observed. Results the age of 10 patients was 2754 years (mean 39.4 years). The clinical symptoms were pelvic mass, exophytic or polypoid growth in ovary, uterine serosa and cervix canal. At the same time, endometriosis or endometrioid cysts coexisted with the corresponding sites. The lesions were composed of benign endometrioid glands and endometrial stroma. The endometrial glands were usually simple hyperplasia, accompanied by fallopian tube mucosal cilia cell metaplasia. Interstitial fibrosis may occur with atypical interstitial cells. All of the 9 patients followed up survived without recurrence. Conclusion Polypoid endometriosis is a special manifestation of endometriosis and is easy to be misdiagnosed as adenosarcoma. The most important significance of understanding this kind of disease lies in avoiding the misjudgment of malignant tumor or other benign neoplastic lesions in postoperative pathological examination, which affects its clinical treatment and treatment.
【作者单位】：复旦大学附属妇产科医院病理科;复旦大学附属妇产科医院超声科;
【分类号】：R711.71

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