年轻女性首次体外受精长方案周期累积活产率相关因素分析

发布时间：2018-08-07 12:40

【摘要】：目的:探讨年轻女性体外受精-胚胎移植(IVF-ET)长方案周期累积活产率的影响因素。方法:回顾性分析首次接受IVF长方案助孕治疗的1 147例年轻且卵巢储备功能良好的不孕女性的临床资料,按完成一次取卵周期是否获得最终活产胎儿分为活产组与未获活产组,采用多因素Logistic回归分析影响累积流产率的相关因素。结果:活产组患者的体质量指数(BMI)较未获活产组显著降低(P0.05),而获卵数、正常受精率及可移植胚胎数显著增高(P0.05)。Logistic回归分析显示BMI及可移植胚胎数是年轻且卵巢储备功能良好的不孕女性首次行IVF长方案周期获得累积活产的重要影响因素,BMI24.2 kg/m2及可移植胚胎数≥5患者的妊娠结局较佳。结论:年轻且卵巢储备功能良好的女性首次IVF长方案周期中,BMI及可移植胚胎数与累积活产率显著相关,较低的BMI及适当多的可移植胚胎数可提高一次取卵周期的累积活产率。
[Abstract]:Aim: to investigate the factors influencing the cumulative long term live births in young women with in vitro fertilization and embryo transfer (IVF-ET). Methods: the clinical data of 1 147 young infertile women with good ovarian reserve function who were first treated with IVF long term regimen were analyzed retrospectively. According to whether the fetuses obtained the final live birth after one cycle of ovulation, they were divided into two groups: live delivery group and non live delivery group. Multivariate Logistic regression analysis was used to analyze the related factors of cumulative abortion rate. Results: the body mass index (BMI) of the patients with live delivery was significantly lower than that of the group without live delivery (P0.05), but the number of eggs obtained was significantly lower than that of the group without live delivery (P0.05). The normal fertilization rate and the number of transferable embryos were significantly increased (P0.05). Logistic regression analysis showed that BMI and the number of transferable embryos were the important factors influencing the cumulative live birth in the first long IVF regimen cycle of young infertile women with good ovarian reserve function. The pregnancy outcome was better in patients with BMI24.2 kg/m2 and number of transferable embryos 鈮，

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