妊娠晚期甘油三酯及总胆固醇对妊娠结局的影响

发布时间：2018-08-07 15:59

【摘要】：目的探讨妊娠晚期甘油三酯(TG)和总胆固醇(TC)水平与不良妊娠结局之间的关系。方法选择妊娠晚期单胎孕妇886例,检测其分娩前一周内的血清TG和TC值,比较样本分布及各组妊娠结局的差异,分析血脂异常程度与新生儿出生体重之间的相关性。结果 1大多数孕妇都有不同程度的血脂升高,以TG升高为主;2当TG水平超过正常值高限两倍时,胎膜早破、产后出血、妊娠期高血压疾病的发生风险明显增加,差异有统计学意义(P0.05);当TG水平超过正常值高限的3倍时,巨大儿、胎膜早破、产后出血、妊娠期高血压疾病的发生率明显增高(P0.05);3高TC组产后出血、肝内胆汁淤积症、妊娠期高血压疾病、早产、妊娠期糖尿病的发生率均明显高于正常TC组(P0.05);4孕晚期母血TG水平与新生儿出生体重呈正相关(r=0.137,P0.05)。结论孕晚期过高的TC、TG水平与不良妊娠结局相关,定期监测血脂水平,加以控制,减少不良妊娠结局的发生。
[Abstract]:Objective to investigate the relationship between the level of triglyceride (TG) and total cholesterol (TC) in the late pregnancy and the outcome of bad pregnancy. Methods 886 pregnant women in the late pregnancy were selected to detect the serum TG and TC values in the first week of delivery, compare the distribution of the samples and the difference of pregnancy outcome, and analyze the difference between the degree of blood lipid abnormality and the birth weight of the newborn. Results 1 of 1 pregnant women have different levels of blood lipid increase, mainly with higher levels of blood lipids, and 2 when the level of TG exceeds the normal limit of two times, the risk of premature rupture of membranes, postpartum hemorrhage, and pregnancy induced hypertension is significantly increased, and the difference is statistically significant (P0.05); when the level of TG exceeds the normal value of the high limit, the giant, fetal membrane The incidence of premature rupture, postpartum hemorrhage, and pregnancy induced hypertension was significantly higher (P0.05); the incidence of postpartum hemorrhage in the 3 high TC group, intrahepatic cholestasis, pregnancy induced hypertension, preterm birth, and gestational diabetes were significantly higher than that of the normal TC group (P0.05), and the level of TG in the late 4 trimester of pregnancy was positively correlated with the birth weight of the newborn (r=0.137, P0.05). Over-high TC and TG levels in late pregnancy are associated with adverse pregnancy outcomes. Regular monitoring of blood lipid levels to control and reduce adverse pregnancy outcomes.
【作者单位】：南京医科大学附属南京妇幼保健院妇产科;
【分类号】：R714

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