音乐刺激孕鼠对子代鼠大脑功能影响的系统评价

发布时间：2018-08-07 16:34

【摘要】：目的系统评价音乐刺激孕鼠对子代鼠大脑功能的影响效果,为促进实验动物的福利以及音乐胎教的应用发展提供科学依据。方法计算机检索Pubmed、Web of Science、Cochrane Library、万方、维普、中国知网和中国生物医学文献数据库,全面收集有关音乐刺激孕鼠对子代鼠大脑功能影响效果的研究文献,检索时限为建库至2016年4月2日。按照纳入与排除标准选择文献、评价文献质量和提取数据,并对数据进行定性描述。结果共纳入7篇实验研究,4篇中文,3篇英文。研究对象均为大鼠,其中5项研究采用Wistar大鼠,2项研究采用SD大鼠。音乐材料涉及舒适音乐、古典音乐、小提琴协奏曲(梁祝),干预周期为妊娠期至分娩期前后不等。研究结果显示:孕期音乐刺激在一定程度上能促进子代大鼠的大脑神经发生,提高空间记忆能力,但对某些功能性受体的表达影响不显著。结论适宜的音乐可以促进子代大鼠大脑功能的发展。
[Abstract]:Objective to evaluate the effects of music stimulation on the brain function of offspring rats and provide scientific basis for promoting the welfare of experimental animals and the application of music fetal education. Methods We searched Pubmedus Web of Science Cochrane Library, Wan Fang, Weip, China knowledge Network and Chinese Biomedical Literature Database, and collected all the literatures about the effect of music stimulation on the brain function of offspring rats. The time limit for retrieval is to build the database until April 2, 2016. According to the inclusion and exclusion criteria, the quality of the literature is evaluated and the data is extracted, and the data is described qualitatively. Results A total of 7 subjects were included in the study, including 4 articles in Chinese and 3 articles in English. All the subjects were rats, of which 5 were Wistar rats and 2 were SD rats. Music materials include comfort music, classical music, violin concerto (Liang Zhu), intervention period from pregnancy to childbirth. The results showed that music stimulation during pregnancy could promote the development of cerebral nerve and improve spatial memory ability in the offspring of rats to a certain extent, but had no significant effect on the expression of some functional receptors. Conclusion suitable music can promote the development of brain function in offspring rats.
【作者单位】：重庆医科大学公共卫生与管理学院;重庆医科大学实验动物中心;
【基金】：重庆市科委应用开发重大项目(cstc2013yykfc10005)
【分类号】：R714.5

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