孕前BMI与胎次对妊娠期高血压疾病影响

发布时间：2018-08-11 16:26

【摘要】：目的探讨胎次与孕前BMI对妊娠期高血压疾病的影响。方法以2011年2月—2012年12月在安徽省合肥市第一人民医院进行孕产期检查并分娩的1 633名孕妇为研究对象,采用2检验和logistic回归模型分析胎次和孕前BMI与妊娠期高血压疾病的关系。结果孕妇孕前BMI均数为(20.20±2.418)kg/m2,消瘦367人(22.5%),正常1 153人(70.6%),超重或肥胖113人(6.9%);第一胎936人(57.3%),第二胎及以上697人(42.7%);单因素logistic回归模型结果显示,孕前超重或肥胖的孕妇第一胎、二胎及以上发生妊娠期高血压疾病的风险均升高(OR=2.722,95%CI=1.074~6.900;OR=4.356,95%CI=1.865~10.171);调整混杂因素孕妇实足年龄、文化程度、工作性质后的多因素logistic回归模型结果显示,胎次是孕前超重或肥胖孕妇患妊娠期高血压疾病的危险因素(第2胎及以上:OR=3.535,95%CI=1.472~8.491,P=0.005)。结论孕前超重及肥胖妇女妊娠胎次越多发生妊娠期高血压疾病的风险越高。
[Abstract]:Objective to investigate the effect of gestational BMI on hypertensive disorder complicating pregnancy. Methods from February 2011 to December 2012, 1 633 pregnant women who were examined and delivered in the first people's Hospital of Hefei, Anhui Province, were studied. 2 test and logistic regression model were used to analyze the relationship between gestational hypertension and BMI before pregnancy. Results the mean BMI before pregnancy was (20.20 卤2.418) kg / m2, the mean value of BMI was (20.20 卤2.418) kg / m ~ (2), the mean value of BMI was (20.20 卤2.418) kg 路m ~ (2), the mean value of BMI was (73.5%), the normal rate was 1 153 (70.6%), the first pregnancy was overweight or obese (6.9%), the first pregnancy was 936 (57.3%), the second was 697 (42.7%), the single factor logistic regression model showed that the first child was overweight or obese before pregnancy. The risk of hypertensive disorder complicating pregnancy was increased in the second trimester and above (OR 2.722 ~ 95 CI 1.074 + 6.900 CI 4.356 + 95 CI 1.865 + 10.171), and the results of multivariate logistic regression model after adjusting for the pregnant women's actual age, education level and nature of work showed that, Birth order was the risk factor of hypertensive disorder complicating pregnancy in overweight or obese pregnant women before pregnancy. Conclusion the risk of hypertensive disorder complicating pregnancy is higher in overweight and obese women before pregnancy.
【作者单位】：安徽医科大学公共卫生学院儿少卫生与妇幼保健学系;安徽人口健康与优生省级实验室;合肥市第一人民医院妇产科;
【基金】：国家自然科学基金(81072310;30901203) 国家科技支撑计划(2006BAI05A03)
【分类号】：R714.246

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