多囊卵巢综合征患者的胰岛素抵抗临床特征及相关因素分析

发布时间：2018-08-14 14:32

【摘要】：目的对多囊卵巢综合征(PCOS)患者胰岛素临床特征及相关因素进行探讨。方法方便选取该院2015年2月—2017年2月收治的PCOS患者86例进行研究,分为观察组与对照组,各43例,对照组为非胰岛素抵抗患者,观察组为胰岛素抵抗患者。对两组患者相关指标进行对比观察,分析相关因素。结果在体质指数、TG、HDL水平方面,观察组分别为(26.83±2.96)kg/m~2、(2.26±0.42)mmol/L、(1.61±0.37)mmol/L,均明显高于对照组,差异有统计学意义(P0.05);在TC、LDL、P、T、E2、PRL、LH、FSH水平方面,两组差异无统计学意义(P0.05);在FPG、FINS、GAUC、HOMA-IR水平方面,观察组分别为(5.23±0.65)mmol/L、(18.77±10.93)m IU/L、(20.53±3.48)、(4.30±2.64),均明显高于对照组,差异有统计学意义(P0.05);对于PCOS胰岛素抵抗患者而言,HOMA-IR与BMI、GAUC呈正相关。结论 PCOS胰岛素抵抗患者HOMA-IR与BMI、GAUC呈正相关,降低患者葡萄糖耐量及肥胖,可使患者发病风险增加。
[Abstract]:Objective to investigate the clinical characteristics and related factors of insulin in patients with polycystic ovary syndrome (PCOS). Methods 86 patients with PCOS admitted in our hospital from February 2015 to February 2017 were divided into two groups: observation group (n = 43) and control group (n = 43). The related indexes of the two groups were compared and the related factors were analyzed. Results in the body mass index (BMI) of TGN HDL, the levels of TGG HDL in the observation group were (26.83 卤2.96) kg / m ~ (-2), (2.26 卤0.42) mmol / L, (1.61 卤0.37) mmol / L, respectively, which were significantly higher than those in the control group (P0.05), the difference was statistically significant (P0.05), but there was no significant difference between the two groups (P0.05) in the level of TCG-LDLPTE2PRLPRLHHHHFSH (P0.05), and in the level of FPGFINSINSUCHOMA-IR, there was no significant difference between the two groups (P0.05). The observed groups were (5.23 卤0.65) mmol / L, (18.77 卤10.93) mmol / L, (20.53 卤3.48), (, 4.30 卤2.64), respectively, which were significantly higher than those in the control group (P0.05), and HOMA-IR was positively correlated with BMIGAUC in patients with insulin resistance of PCOS. Conclusion there is a positive correlation between HOMA-IR and BMI-GAUC in patients with PCOS insulin resistance.
【作者单位】：昆明市妇幼保健院妇科
【分类号】：R711.75

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