妊娠期糖尿病患者骨密度检测及影响因素分析

发布时间：2018-08-19 11:33

【摘要】：目的探讨妊娠期糖尿病患者骨密度情况及影响因素。方法选择2007年12月至2012年5月在孝感市中心医院产检和住院的孕妇,其中,正常孕妇160例为对照组,临床确诊为GDM的患者156例,应用超声骨密度测定仪测定孕妇右侧跟骨骨密度,检测空腹血糖(FPG)、糖化血红蛋白(Hb A1C),并进行统计学分析。结果妊娠期糖尿病组孕妇骨密度检测结果中BUA、SOS、SI均明显低于对照组(P0.05);妊娠期糖尿病组骨量减少、骨质疏松比例分别为15.38%、5.13%,明显高于对照组(P0.05);Pearson相关分析显示SI与年龄、孕周、FBS、Hb A1C呈负相关(r=-0.160、-0.265、-0.160和-0.156,P0.05),与BMI呈正相关(r=0.069,P0.05)。结论妊娠期糖尿病患者骨量减少及骨质疏松发生率较正常孕妇明显升高;且跟骨超声骨密度SI与年龄、孕周、FBS、Hb A1C呈负相关,与BMI呈正相关。
[Abstract]:Objective to investigate the bone mineral density (BMD) of gestational diabetes mellitus (GDM) and its influencing factors. Methods from December 2007 to May 2012, 160 normal pregnant women were selected as the control group and 156 patients with GDM as the control group, who were examined and hospitalized in Xiaogan Central Hospital from December 2007 to May 2012. Bone mineral density (BMD) of right calcaneus and fasting blood glucose (FBG) (FPG), glycosylated hemoglobin (HbA1C) were measured by ultrasonic absorptiometry. Results the bone mineral density of pregnant women with gestational diabetes mellitus was significantly lower than that of the control group (P0.05), and the ratio of bone mass and osteoporosis in gestational diabetes mellitus group was 15.385.13, which was significantly higher than that in the control group (P0.05). There was a negative correlation between HbA1C and BMI (r = 0.160, P < 0.05), and a positive correlation with BMI (r = 0.069, P 0.05). Conclusion the incidence of osteopenia and osteoporosis in patients with gestational diabetes mellitus is significantly higher than that in normal pregnant women, and the ultrasonic bone density SI of calcaneus is negatively correlated with age, FBSS-HbA1C, and is positively correlated with BMI.
【作者单位】：湖北省孝感市中心医院妇产科;
【分类号】：R714.256

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