复发性流产患者综合保胎治疗成功后母婴结局分析

发布时间：2018-08-29 13:58

【摘要】：目的:对复发性流产(RSA)综合保胎治疗成功患者进行回顾性分析,对母婴安全性进行评估。方法:选择天津医科大学宝坻临床学院(我院)2012年6月—2015年6月,年龄小于35岁,孕早期住院予综合保胎治疗成功的,并且于我院分娩的RSA患者105例作为研究对象(观察组);选择同期无自然流产史、未经保胎治疗于我院分娩的孕妇105例作为对照组。观察2组产妇妊娠并发症、出血、羊水、胎儿、新生儿情况,新生儿随访至生后12周。结果:观察组妊娠期高血压、胎膜早破发生率低于对照组,差异有统计学意义(均P0.05)。2组产妇妊娠期糖尿病、前置胎盘、产后出血发生率差异无统计学意义(均P0.05)。排除死胎及畸形引产,2组产妇出血量、羊水情况评分比较差异无统计学意义(均P0.05)。2组新生儿评分,性别比,早产、巨大儿、新生儿出生缺陷、12周黄疸发生率差异均无统计学意义(均P0.05)。2组产妇足月分娩孕周和孕足月新生儿出生体质量比较差异无统计学意义(均P0.05)。结论:RSA综合保胎治疗安全有效,未发现对母婴产生不良影响,可以临床推广。
[Abstract]:Objective: to evaluate the safety of (RSA) for recurrent abortion. Methods: from June 2012 to June 2015, Baodi Clinical College of Tianjin Medical University, aged less than 35 years, was selected to be hospitalized in early pregnancy and successfully treated with comprehensive fetal preservation. 105 cases of RSA patients in our hospital were chosen as the study object (observation group), and 105 cases of pregnant women who had no history of spontaneous abortion and had not been treated with fetal protection were selected as the control group. Pregnancy complications, hemorrhage, amniotic fluid, fetus and newborn were observed in both groups. The neonates were followed up to 12 weeks after birth. Results: the incidence of hypertension and premature rupture of membranes in the observation group was lower than that in the control group (P0.05). There was no significant difference in the incidence of gestational diabetes mellitus, placenta previa and postpartum hemorrhage in the observation group (P0.05). There was no significant difference in blood loss and amniotic fluid score between the two groups excluding stillbirth and abnormal induced labor (P0.05). There was no significant difference in the incidence of jaundice at the 12th week of neonatal birth defect (P0.05). 2. There was no significant difference in the birth weight of full-term delivery and gestational term newborns in group 2 (P0.05). Conclusion it is safe and effective to treat the fetus with: RSA, no adverse effect on mother and child has been found, and can be popularized in clinic.
【作者单位】：天津医科大学总医院;天津医科大学宝坻临床学院;
【分类号】：R714.21

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