妊娠子痫前期发病的相关因素分析

发布时间：2018-08-31 17:36

【摘要】：目的探讨妊娠子痫前期(PECL)发病的相关因素。方法将193例妊娠期高血压(GHP)患者按是否并发PECL分为GHP组与PECL组,收集两组临床资料,比较两组年龄、孕周、体质量指数(BMI)、血红蛋白、血小板、血肌酐、血尿酸、24 h尿蛋白、高血压家族史、收缩压、舒张压及平均动脉压(MAP)的差异,分析PECL发病的相关因素。结果与GHP组比较,PECL组年龄、血红蛋白、血小板数明显低(P均0.05),BMI、血肌酐、血尿酸、24h尿蛋白、收缩压、舒张压及MAP明显高,有高血压家族史者多(P均0.05)。多因素Logistic回归分析显示,血小板与PECL发病呈负相关(r=-0.07,P0.05),是PECL发病的保护因素,而血尿酸、高血压家族史与PECL发病呈正相关(r分别为0.14、1.12,P均0.05),是PECL发生的危险因素。结论 PECL发病与孕妇年龄、营养状态等多个因素有关,而血小板、血尿酸水平及高血压病家族史是PECL发病的独立因素。
[Abstract]:Objective to investigate the related factors of (PECL) in preeclampsia. Methods 193 cases of hypertensive (GHP) complicating pregnancy were divided into GHP group and PECL group according to whether they were complicated with PECL. The clinical data of the two groups were collected and compared in age, gestational week, body mass index (BMI),) hemoglobin, platelet, serum creatinine and uric acid 24 h urine protein. Family history of hypertension, systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean arterial pressure (MAP) were analyzed. Results compared with GHP group, age, hemoglobin and platelet count were significantly lower (P < 0. 05), serum creatinine, 24 h urinary protein, systolic blood pressure, diastolic blood pressure and MAP were significantly higher in PECL group than those in GHP group (P 0. 05). Multivariate Logistic regression analysis showed that there was a negative correlation between platelet and PECL (r = 0.07, P 0.05), which was the protective factor of PECL, while serum uric acid and family history of hypertension were positively correlated with the incidence of PECL (r = 0.14, 1.12, P 0.05, respectively), which were the risk factors of PECL. Conclusion the incidence of PECL is related to the age and nutritional status of pregnant women, while platelet, serum uric acid level and family history of hypertension are independent factors of PECL.
【作者单位】：铜陵市妇幼保健院;安徽医科大学第二附属医院;
【分类号】：R714.244

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