不明原因复发性流产患者生化妊娠史与妊娠结局关系的研究

发布时间：2018-09-01 11:31

【摘要】：目的探讨不明原因复发性流产(URSA)患者的生化妊娠史与妊娠结局的关系。方法选取URSA患者192例,根据既往生化妊娠次数,分为无生化妊娠组(A组)66例,1次生化妊娠组(B组)65例,≥2次生化妊娠组(C组)61例。分析并比较3组患者的临床特征及妊娠结局。结果 C组与A组及B组比较,既往自然流产次数(P0.05)、既往体外受精和胚胎移植自然流产率(P0.012 5)均显著增高,其自然流产率及自然流产伴正常染色体核型(SANK)率也均显著增高(P0.012 5)。A组与B组比较,活产率、自然流产率及SANK率差别均无统计学意义(P0.012 5)。结论≥2次生化妊娠的患者既往复发性流产更为严重,保胎治疗后其活产率较低、自然流产和SANK风险较高。
[Abstract]:Objective to investigate the relationship between biochemical pregnancy history and pregnancy outcome in (URSA) patients with recurrent abortion of unknown cause. Methods 192 patients with URSA were divided into two groups: group A (n = 66), group B (n = 66) and group C (n = 61). The clinical characteristics and pregnancy outcome of three groups were analyzed and compared. Results compared with group A and group B, the number of previous spontaneous abortion (P0.05), the rate of spontaneous abortion of in vitro fertilization and embryo transfer (P0.0125) in group C were significantly higher than those in group A and B (P0.0125). The rate of spontaneous abortion and the (SANK) rate of normal chromosome karyotype in group A were significantly higher than those in group B (P0.0125). There was no significant difference in live rate, spontaneous abortion rate and SANK rate between group A and group B (P0.0125). Conclusion the recurrent abortion is more serious in the patients with 鈮，

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