月经期取卵在卵巢低储备患者IVF-ET中的应用
发布时间:2018-09-02 08:21
【摘要】:目的:探讨月经期取卵在卵巢低储备(diminished ovarian reserve,DOR)患者体外受精-胚胎移植(IVF-ET)中应用的可行性。方法:回顾性分析70例DOR行IVF/卵胞质单精子注射(ICSI)-ET治疗的不孕症患者的临床资料,比较其73个月经期取卵和270个非月经期取卵的结局。若月经2~4 d阴道超声提示优势卵泡直径≥14 mm且E2水平200 ng/L则行月经期取卵,若无优势卵泡按常规促排卵方案行IVF/ICSI,观察其临床结局。结果:月经期组获卵数、成熟卵数和可用胚胎数分别为1.0±0.4个、0.8±0.4个、0(0,1)个,非月经期组分为1.6±1.2个、1.4±1.1个、1(0,1)个,组间有统计学差异(P0.05)。月经期组周期取消率为72.6%,显著高于非月经期组43.0%(P0.05)。月经期组获卵率、卵裂率、卵子利用率分别为83.1%、94.7%和34.5%,非月经期组分别为70.6%、96.7%和51.7%,组间无统计学差异(P0.05)。结论:尽管月经期取卵的获卵数、成熟卵数、可用胚胎数小于非月经期取卵,但获卵率、卵裂率和卵子利用率组间无统计学差异,为反复周期取消、高基础雌激素的DOR不孕症患者节约了治疗时间,提供了新的方法。
[Abstract]:Objective: to investigate the feasibility of in vitro fertilization and embryo transfer (IVF-ET) in patients with low reserve (diminished ovarian reserve,DOR. Methods: the clinical data of 70 patients with infertility treated with IVF/ oocyte sperm injection (ICSI)-et in DOR were retrospectively analyzed, and the outcomes of 73 months oocyte extraction and 270 non-menstrual period oocytes were compared. If the dominant follicle diameter 鈮,
本文编号:2218801
[Abstract]:Objective: to investigate the feasibility of in vitro fertilization and embryo transfer (IVF-ET) in patients with low reserve (diminished ovarian reserve,DOR. Methods: the clinical data of 70 patients with infertility treated with IVF/ oocyte sperm injection (ICSI)-et in DOR were retrospectively analyzed, and the outcomes of 73 months oocyte extraction and 270 non-menstrual period oocytes were compared. If the dominant follicle diameter 鈮,
本文编号:2218801
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