血清β-HCG与h-CRP和CRP对胎膜早破孕妇宫内感染的预测价值分析

发布时间：2018-09-08 07:39

【摘要】：目的探究血清β-HCG、超敏C-反应蛋白(h-CRP)和C-反应蛋白(CRP)水平对胎膜早破患者宫内感染的预测价值,以期提升胎膜早破孕妇的预后质量。方法选择2015年2月-2016年2月医院收治的42例胎膜早破孕妇作为研究对象,检测所有孕妇血清β-HCG、h-CRP和CRP水平,以胎膜病理检测结果为金标准,计算血清β-HCG、h-CRP和CRP诊断宫内感染的敏感性、特异性、准确度。结果受试者工作曲线结果显示,血清β-HCG、h-CRP、CRP宫内感染的临界值分别为:2.09ng/ml,3.69mg/L,0.11g/L;血清β-HCG+h-CRP、β-HCG+h-CRP+CRP的灵敏度、特异度和准确度分别为:80.00%、91.67%、83.33%、83.33%、91.67%、85.71%,明显优于其它组合或者单一指标预测。结论血清β-HCG+h-CRP+CRP三者联合预测胎膜早破孕妇是否并发宫内感染具有较高的临床价值,为临床治疗措施选择提供重要信息,促进胎膜早破孕妇母儿安全具有重要临床价值。
[Abstract]:Objective to investigate the predictive value of serum 尾 -HCG, hypersensitive C-reactive protein (h-CRP) and C-reactive protein (CRP) on intrauterine infection in patients with premature rupture of membranes in order to improve the quality of prognosis of pregnant women with premature rupture of membranes. Methods from February 2015 to February 2016, 42 pregnant women with premature rupture of membranes were selected as the study subjects. The serum levels of 尾 -HCGfen-CRP and CRP were measured in all pregnant women, and the results of fetal membrane pathology were taken as the gold standard. The sensitivity, specificity and accuracy of serum 尾 -HCGG h-CRP and CRP in the diagnosis of intrauterine infection were calculated. Results the results of the operating curve showed that the critical values of serum 尾 -HCG h-CRPU CRP intrauterine infection were: 1 / 2.09 ng / ml, 3.69 mg / L / L respectively, and the sensitivity, specificity and accuracy of serum 尾 -HCG h-CRP, 尾 -HCG h-CRP CRP were 80.0091.67 ~ 83.33 ~ 83.33 ~ 83.33 ~ 83.33 ~ 83.33 ~ 83.33 / 85.71, respectively, which were better than those of other combinations or a single index in predicting the intrauterine infection of 尾 -HCG h-CRP, 尾 -HCG, 尾 -HCG, 尾 -HCG, 尾 -HCG and 尾 -HCG h-CRP CRP. Conclusion the combination of serum 尾 -HCG and h-CRP CRP is of high clinical value in predicting intrauterine infection in pregnant women with premature rupture of membranes, which provides important information for the choice of clinical treatment measures and promotes the safety of pregnant women with premature rupture of membranes.
【作者单位】：郑州市第七人民医院产科;
【分类号】：R714.433

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