妇科围术期静脉血栓形成的危险因素评估

发布时间：2018-09-08 08:43

【摘要】：目的探讨妇科围术期静脉血栓形成的危险因素。方法回顾分析1 970例北京大学深圳医院妇科术后患者临床资料,采用统计学方法分析患者存在的危险因素与静脉血栓形成的关系。结果 1 970例手术患者中,发病患者13例,发病率为0.7%。其中,恶性肿瘤患者发病11例,占84.6%。单因素分析中,患者年龄、糖尿病、恶性肿瘤、肿瘤期别、深间质浸润、分化程度、肿瘤转移、手术方式、手术时间、术中出血量、输血与患者静脉血栓发生有关,差异有统计学意义(P0.05)。多因素分析中,恶性肿瘤晚期、低分化是静脉血栓形成的相关危险因素,差异有统计学意义(P0.05)。结论年龄及糖尿病史、恶性肿瘤、手术情况与围术期静脉血栓形成有密切关系,肿瘤分期及分化程度可能是静脉血栓形成的独立危险因素。
[Abstract]:Objective to investigate the risk factors of venous thrombosis in gynecological perioperative period. Methods the clinical data of 1 970 patients after gynecological surgery in Shenzhen Hospital of Peking University were retrospectively analyzed. The relationship between the risk factors and venous thrombosis was analyzed statistically. Results of the 1,970 patients, 13 were involved, and the incidence rate was 0.7. Among them, 11 cases (84.6%) had malignant tumor. In univariate analysis, age, diabetes, malignant tumor, tumor stage, deep interstitial infiltration, differentiation degree, tumor metastasis, operation mode, operative time, intraoperative blood loss and blood transfusion were associated with venous thrombosis. The difference was statistically significant (P0.05). In multivariate analysis, late malignant tumor, low differentiation is the risk factor of venous thrombosis, the difference is statistically significant (P0.05). Conclusion Age, history of diabetes, malignant tumor and operation are closely related to venous thrombosis in perioperative period. Tumor staging and differentiation may be independent risk factors for venous thrombosis.
【作者单位】：北京大学深圳医院妇科深圳女性重大疾病早期诊断技术重点实验室;
【基金】：深圳市科技创新项目(201302060)
【分类号】：R713

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