阿司匹林联合低分子肝素治疗血栓前状态致复发性流产84例临床分析

发布时间：2018-10-05 08:37

【摘要】：目的探讨血栓前状态致复发性流产的临床危害和诊疗方法。方法选择84例血栓前状态致复发性流产患者随机分为两组,应用阿司匹林治疗组(对照组)42例,阿司匹林联合低分子肝素治疗组(观察组)42例,比较两组患者治疗前、后的流产率、早产率、足月产率的妊娠结局;对两组孕妇治疗前、后抗凝血酶Ⅲ、D-二聚体、凝血酶时间等指标进行检验比较以及两组在出血、血小板减少、瘀斑等不良反应的发生进行比较。结果两组流产率、早产率、足月产率的妊娠结局比较差异有统计学意义(P0.05);两组患者治疗前、后D-二聚体、抗凝血酶Ⅲ(AT-Ⅲ)、凝血酶时间(TT)等血栓性检验指标比较差异有统计学意义(P0.05);两组患者治疗前、后出血、血小板减少、瘀斑等不良反应的发生率比较差异无统计学意义(P0.05)。结论阿司匹林联合低分子肝素治疗由血栓前状态导致的复发性流产有良好的临床意义。
[Abstract]:Objective to investigate the clinical harm and diagnosis and treatment of recurrent abortion caused by prethrombotic state. Methods Eighty-four patients with recurrent abortion caused by prethrombotic state were randomly divided into two groups: the control group (n = 42) and the control group (n = 42). The pregnancy outcome of abortion rate, preterm delivery rate and term delivery rate after treatment were compared between the two groups of pregnant women before and after treatment of anti-thrombin 鈪，

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