236例卵巢上皮性癌临床分析
发布时间:2018-10-07 19:45
【摘要】:目的: 本次研究回顾性分析卵巢上皮性癌患者的一般诊疗过程,及对单因素和多因素分析进一步探讨卵巢上皮性癌的相关预后因素。 方法: 收集病例为2006年-2011年于吉林大学第一医院妇科初治的上皮性卵巢癌患者的临床资料,分析该病临床特点及发病年龄、临床分期、病理类型、手术方式、术后化疗次数等与预后的相关性。 结果: 1、236例患者发病平均年龄52.0岁,发病高峰年龄为50-59岁,共93例。2、早期患者的临床表现主要为腹痛症状(40.85%);而晚期患者的临床表现多集中在消化系统症状(69.09%)。3、单因素分析显示年龄≥50岁,已绝经者,妊娠次数<3次,生产次数<2次,临床分期晚期、病理类型浆液性、初次术后残留病灶大小≥2cm及化疗次数<6次患者预后差(P<0.05)。初潮年龄、组织分化对预后无明显关系。4、多因素分析显示妊娠次数、临床分期、病理类型、初次术后残留病灶大小及化疗次数是影响卵巢上皮性癌的独立预后因素(P<0.05)。 结论: 1、50-59岁为卵巢上皮性癌发病高峰年龄。2、对于出现腹胀等消化系统症状患者及时进行超声检查及CA125、HE4等肿瘤标志物检测,可作为筛查卵巢恶性肿瘤的常规检测手段。3、妇科查体作为肿瘤妇科医师必不可少的技能应受到充分的重视。4、在行子宫切除时应同时切除双侧输卵管,尤其对于已完成生育功能且具有卵巢癌家族史的患者应切除双侧输卵管以降低卵巢癌发病。5、绝经年龄及生产次数是影响卵巢上皮性癌的危险因素,,而初潮年龄、组织分化对预后无明显关系。6、妊娠次数、临床分期、病理类型、初次术后残留病灶大小及化疗次数可明显影响卵巢上皮性癌的预后。
[Abstract]:Objective: to analyze the general diagnosis and treatment process of ovarian epithelial carcinoma and to explore the prognostic factors of ovarian epithelial carcinoma by univariate and multivariate analysis. Methods: the clinical data of patients with epithelial ovarian cancer were collected from 2006 to 2011 in the first Hospital of Jilin University. The correlation between postoperative chemotherapeutic frequency and prognosis. Results: the mean age of 1236 patients was 52.0 years old, the peak age was 50-59 years old, 93 cases were .2.The main clinical manifestations of early patients were abdominal pain (40.85%). The clinical manifestations of the late stage patients were mainly digestive system symptoms (69.09%) .3The univariate analysis showed that the age 鈮
本文编号:2255446
[Abstract]:Objective: to analyze the general diagnosis and treatment process of ovarian epithelial carcinoma and to explore the prognostic factors of ovarian epithelial carcinoma by univariate and multivariate analysis. Methods: the clinical data of patients with epithelial ovarian cancer were collected from 2006 to 2011 in the first Hospital of Jilin University. The correlation between postoperative chemotherapeutic frequency and prognosis. Results: the mean age of 1236 patients was 52.0 years old, the peak age was 50-59 years old, 93 cases were .2.The main clinical manifestations of early patients were abdominal pain (40.85%). The clinical manifestations of the late stage patients were mainly digestive system symptoms (69.09%) .3The univariate analysis showed that the age 鈮
本文编号:2255446
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