宫颈TCT,高危型HPV及阴道镜下宫颈活检对宫颈病变的筛查价值
发布时间：2018-10-08 07:50
【摘要】：目的探讨液基细胞学检查(TCT)、高危型人乳头状瘤病毒DNA(HPV-DNA)及联合检测对宫颈病变筛查的临床应用价值。方法接受宫颈病变筛查的926例患者进行TCT、HPV-DNA检测,异常者予阴道镜下活检确诊。结果 926例患者经病理检查826例确诊为无内皮病变(NILM)者,TCT检测阳性率为17.07%,25确诊为宫颈上皮内瘤变(CIN)I,TCT检测阳性率为72.35%,75例确诊为≥CIN II,TCT检测阳性率为89.33%,HPV-DNA检测阳性225例。同时HPVDNA特异性、灵敏性、漏诊率、误诊率分别为82.93%、65.00%、35.00%、17.07%;TCT特异性、灵敏性、漏诊率、误诊率分别为82.08%、66.00%、34.00%、17.92%;二者联合特异性、灵敏性、漏诊率、误诊率分别为97.58%、98.00%、2.00%、2.42%。结论临床应用宫颈TCT、HPV-DNA、阴道镜下活检进行宫颈病变早期筛查是一种有效、可行的筛查方案,可有效提高宫颈病变检出率,对宫颈癌的早期诊断与治疗有着重要的临床意义。
[Abstract]:Objective to evaluate the clinical value of liquid-based cytologic examination of high-risk human papillomavirus (HPV-DNA) DNA (HPV-DNA) in screening cervical lesions. Methods TCT,HPV-DNA was detected in 926 patients with cervical lesions, and the abnormal cases were diagnosed by colposcopy biopsy. Results the positive rate of (NILM) in 926 patients with no (NILM) was 17.0725. The positive rate of TCT was 72.35%. 75 cases were diagnosed as 鈮，
本文编号：2255992
[Abstract]:Objective to evaluate the clinical value of liquid-based cytologic examination of high-risk human papillomavirus (HPV-DNA) DNA (HPV-DNA) in screening cervical lesions. Methods TCT,HPV-DNA was detected in 926 patients with cervical lesions, and the abnormal cases were diagnosed by colposcopy biopsy. Results the positive rate of (NILM) in 926 patients with no (NILM) was 17.0725. The positive rate of TCT was 72.35%. 75 cases were diagnosed as 鈮，
本文编号：2255992
本文链接：https://www.wllwen.com/yixuelunwen/fuchankeerkelunwen/2255992.html
最近更新
教材专著
