薄型子宫内膜合并甲状腺功能减退不孕患者的辅助生育治疗结局
发布时间：2018-10-12 19:31
【摘要】：目的探讨薄型子宫内膜合并甲状腺功能减退不孕患者行辅助生育治疗后的效果。方法 165例因新鲜周期内膜≤7 mm而取消胚胎移植的不孕患者,在拟行冻融胚胎移植前,对游离甲状腺素T4(FT4)正常、促甲状腺激素(TSH)2.5 mIU/L的患者进行左旋甲状腺素片干预治疗。经治疗4~8周后,患者依据TSH水平分为A组(n=70),TSH2.5 mIU/L;B组(n=95),TSH≤2.5 mIU/L。所有患者均采用相同剂量激素替代方案准备子宫内膜,分析子宫内膜情况及辅助生育结局。结果 A组与B组相比,虽然子宫内膜下血流数量和阻力指数(RI)组间无统计学差异(P0.05),但B组内膜下血流数量的均值高于A组,RI均值低于A组。且B组的子宫内膜厚度、临床妊娠率显著高于A组(P0.05),流产率显著低于A组(P0.05)。结论薄型子宫内膜合并TSH升高的不孕患者,给予干预至TSH2.5 mIU/L后,行辅助生育治疗可改善这些患者的妊娠结局。
[Abstract]:Objective to investigate the effect of assisted fertility therapy in infertile patients with thin endometrium complicated with hypothyroidism. Methods 165 infertile patients whose fresh endometrium was less than 7 mm were treated with levothyroxine tablet before freeze-thawing embryo transfer. The free thyroxine T4 (FT4) was normal and the thyroid stimulating hormone (TSH) was 2.5 mIU/L. After 4 weeks of treatment, patients were divided into two groups according to TSH level: group A (n = 70) and group TSH2.5 mIU/L;B (n = 95), TSH 鈮，
本文编号：2267333
[Abstract]:Objective to investigate the effect of assisted fertility therapy in infertile patients with thin endometrium complicated with hypothyroidism. Methods 165 infertile patients whose fresh endometrium was less than 7 mm were treated with levothyroxine tablet before freeze-thawing embryo transfer. The free thyroxine T4 (FT4) was normal and the thyroid stimulating hormone (TSH) was 2.5 mIU/L. After 4 weeks of treatment, patients were divided into two groups according to TSH level: group A (n = 70) and group TSH2.5 mIU/L;B (n = 95), TSH 鈮，
本文编号：2267333
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