重度子痫前期患者血清尿素氮、肌酐、尿酸水平变化

发布时间：2018-10-23 17:34

【摘要】：目的观察重度子痫前期(SPE)患者血清尿素氮(BUN)、肌酐(Cr)、尿酸(UA)水平变化。方法 50例SPE患者(A组)、50例妊娠合并慢性高血压的孕妇(B组)、正常孕妇50例(对照组)。抽取三组晨起空腹静脉血5mL,采用罗氏cobas8000全自动生化分析仪测定血清BUN、Cr、UA。结果 A、B、对照组血清BUN分别为(3.74±4.29)、(3.29±0.99)、(4.02±1.16)mmol/L,组间两两比较,P均0.05。A、B、对照组血清Cr分别为(53.69±11.63)、(57.24±11.07)、(54.07±9.72)μmol/L,组间两两比较,P均0.05。A、B、对照组血清UA分别为(228.67±48.80)、(223.82±67.56)、(182.34±42.96)μmol/L,组间两两比较,P均0.05。结论 SPE患者血清UA水平升高。UA可能参与了SPE的发生。
[Abstract]:Objective to observe the changes of serum urea nitrogen (BUN), creatinine (Cr), uric acid (UA) in patients with severe preeclampsia (SPE). Methods 50 SPE patients (group A), 50 pregnant women with chronic hypertension (group B) and 50 normal pregnant women (control group). Serum BUN,Cr,UA. was measured by Roche cobas8000 automatic biochemistry analyzer after 5 mL of fasting venous blood was taken from three groups in the morning. Results the serum BUN of the control group was (3.74 卤4.29), (卤0.99), (4.02 卤1.16) mmol/L, (P < 0.05), the serum Cr of the control group was (53.69 卤11.63), () 54.07 卤9.72 渭 mol/L, (P < 0.05), and the serum UA of the control group was (228.67 卤48.80), (223.82 卤67.56), (182.34 卤42.96) 渭 mol/L, (P < 0.05). Conclusion the level of serum UA in patients with SPE is increased. UA may be involved in the pathogenesis of SPE.
【作者单位】：天津市第五中心医院;
【基金】：天津市滨海新区卫生计生委科技项目(2015BWKZ003)
【分类号】：R714.244

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