妇乐颗粒联合左氧氟沙星和甲硝唑治疗急性盆腔炎的临床研究

发布时间：2018-11-02 10:17

【摘要】：目的探讨妇乐颗粒联合左氧氟沙星和甲硝唑治疗急性盆腔炎的临床疗效。方法选取2015年2月—2016年2月在屯昌县人民医院接受治疗的急性盆腔炎患者86例,按照治疗方法的差别分为对照组和治疗组,每组各43例。对照组患者静脉滴注盐酸左氧氟沙星氯化钠注射液,0.5 g/次,2次/d;并静脉滴注甲硝唑氯化钠注射,0.5 g/次,2次/d。治疗组在对照组基础上口服妇乐颗粒,2袋/次,2次/d。两组患者均治疗10 d。观察两组的临床疗效,比较两组的炎症因子、临床症状消失时间和临床症状评分情况。结果治疗后,对照组和治疗组的总有效率分别为81.40%、95.35%,两组比较差异有统计学意义(P0.05)。治疗后,两组hs-CRP、IL-6和TNF-ɑ均显著降低,同组治疗前后比较差异有统计学意义(P0.05);且治疗组这些观察指标的降低程度明显优于对照组,两组比较差异具有统计学意义(P0.05)。治疗后,治疗组体温降至正常时间、下腹痛消失时间和阴道分泌物增多的消失时间均短于对照组,两组比较差异有统计学意义(P0.05)。治疗后,两组小腹疼痛、带下量多和腰骶胀痛评分均显著降低,同组治疗前后比较差异有统计学意义(P0.05);且治疗组这些观察指标的下降程度明显优于对照组,两组比较差异具有统计学意义(P0.05)。结论妇乐颗粒联合左氧氟沙星和甲硝唑治疗急性盆腔炎具有较好的临床疗效,可改善临床症状,降低炎性症反应,具有一定的临床推广应用价值。
[Abstract]:Objective to investigate the clinical effect of fule granule combined with levofloxacin and metronidazole in the treatment of acute pelvic inflammatory disease. Methods 86 patients with acute pelvic inflammatory disease received treatment in Tunchang people's Hospital from February 2015 to February 2016 were divided into control group (n = 43) and treatment group (n = 43) according to the difference of treatment methods. Patients in control group were treated with levofloxacin hydrochloride sodium chloride injection (0.5 g / time, twice a day) and metronidazole sodium chloride injection (0.5 g / time, 2 times / d). Treatment group on the basis of the control group oral Fu Le granule, 2 bags per time, 2 times per day. Both groups were treated for 10 days. To observe the clinical effect of the two groups, to compare the inflammatory factors, the time of disappearance of clinical symptoms and the clinical symptom score between the two groups. Results after treatment, the total effective rates of the control group and the treatment group were 81.40 and 95.355.The difference between the two groups was statistically significant (P0.05). After treatment, the hs-CRP,IL-6 and TNF- of the two groups were significantly decreased, the difference between the same group before and after treatment was statistically significant (P0.05). The decrease of these indexes in the treatment group was significantly better than that in the control group, and the difference between the two groups was statistically significant (P0.05). After treatment, the body temperature of the treatment group dropped to normal time, the disappearance time of lower abdominal pain and vaginal discharge increased were shorter than that of the control group, the difference between the two groups was statistically significant (P0.05). After treatment, the two groups of abdominal pain, more under the belt and lumbosacral distending pain score were significantly decreased, the same group before and after treatment compared with statistical significance (P0.05); The decrease of these indexes in the treatment group was significantly better than that in the control group, and the difference between the two groups was statistically significant (P0.05). Conclusion Fule granule combined with levofloxacin and metronidazole has a good clinical effect on acute pelvic inflammatory disease, can improve clinical symptoms and reduce inflammatory reaction, and has a certain clinical application value.
【作者单位】：屯昌县人民医院妇产科;
【分类号】：R711.33

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