孕激素后半周期治疗在功血治疗中的应用

发布时间：2018-11-08 11:25

【摘要】：目的分析孕激素后半周期治疗在功血治疗中的应用。方法选取2014年9月—2015年6月期间该院收治的60例围绝经期功能失调性子宫出血患者,将所有患者随机分为两组,各30例,对照组在刮宫后采用达英-35治疗,观察组则采用安宫黄体酮治疗,分析比较两组治疗有效率、疾病复发率、在治疗期间出现的不规律出血、服药3周后经量恢复正常率及子宫内膜厚度变化。结果观察组治疗有效率为76.67%,低于对照组93.33%,P0.05差异有统计学意义;观察组治疗期间的不规律的出血率为26.67%及服药3周后经量恢复正常率为86.67%均高于对照组10.00%和46.67%,P0.05,差异有统计学意义;两组治疗后疾病复发率对比,差异无统计学意义,P0.05;治疗前,观察组子宫内膜厚度为(12.27±1.53)mm与对照组(12.31±1.26)mm比较,差异无统计学意义,P0.05;治疗后,观察组子宫内膜厚度(5.26±1.48)mm低于对照组(7.83±1.12)mm,差异有统计学意义,P0.05;观察组并发症发生率为23.33%,显著高于对照组6.67%,P0.05差异有统计学意义。结论安宫黄体酮及达英-35在治疗功血中均可有效控制患者出血量及子宫内膜厚度,使患者血液中血红蛋白含量升高,相对而言,达英-35安全性较高。
[Abstract]:Objective to analyze the application of progesterone posterior half-cycle therapy in the treatment of dysfunctional blood. Methods from September 2014 to June 2015, 60 patients with peri menopausal dysfunctional uterine bleeding were randomly divided into two groups: 30 patients in each group. The control group was treated with Dain-35 after curettage. The observation group was treated with progesterone. The effective rate, recurrence rate, irregular bleeding during treatment were analyzed and compared between the two groups. After 3 weeks of medication, the volume returned to normal and the endometrial thickness changed. Results the effective rate of treatment in the observation group was 76.67, which was significantly lower than that in the control group 93.33 (P0.05). The rate of irregular bleeding was 26.67% in the observation group and 86.67% in the control group after 3 weeks of medication, which was significantly higher than that in the control group (10.00%) and 46.67% (P0.05). Before treatment, the endometrial thickness of the observation group was (12.27 卤1.53) mm compared with the control group (12.31 卤1.26) mm, the difference was not statistically significant (P 0.05). After treatment, the endometrial thickness in the observation group (5.26 卤1.48) mm was significantly lower than that in the control group (7.83 卤1.12) mm, P 0.05; The incidence of complications in the observation group was 23.33, which was significantly higher than that in the control group (6.67%, P0.05). Conclusion both progesterone and diane-35 can effectively control the blood loss and endometrial thickness and increase the hemoglobin content in the blood of the patients, and the safety of dioxin 35 is relatively high.
【作者单位】：周口市中心医院妇科;
【分类号】：R711.52

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