子宫内膜厚度差预测IVF-ET妊娠结局的临床观察

发布时间：2018-11-10 07:18

【摘要】：目的:探讨hCG注射日子宫内膜上段和中段2个测量点的厚度之差与体外受精-胚胎移植(IVF-ET)妊娠结局之间的相关关系。方法:对初次接受IVF-ET治疗的256例患者,在hCG注射日行阴道超声测量子宫内膜最大厚度、上段厚度(距宫底10 mm处)、中段厚度(距宫底20 mm处)、上中段内膜差(ETD,即上段厚度-中段厚度)。根据ETD将患者分为4组:A组(ETD0 mm);B组(ETD 0~2.0 mm);C组(ETD 2.1~4.0 mm);D组(ETD4.0 mm),然后以年龄35岁为界将患者分为2个亚组:≥35岁和35岁,比较各组的临床妊娠率、胚胎着床率和继续妊娠率。结果:年龄35岁患者总的临床妊娠率为59.16%,4组胚胎着床率分别是39.3%、38.3%、51.2%和27.5%,4组之间有统计学差异(P=0.038 6)。4组的临床妊娠率为59.1%、60.6%、67.7%和45.0%(P=0.525);继续妊娠率为52.3%、50.0%、54.1%和30.0%,C组高于其余各组,但无统计学差异(P=0.296)。年龄≥35岁患者临床妊娠率为43.8%,较35岁者低,且不同ETD组间各种观察数据无统计学差异(P0.05)。结论:年轻患者ETD在2.1~4.0 mm范围时可能预示更佳的妊娠结局。
[Abstract]:Aim: to investigate the relationship between the thickness difference between the upper and middle endometrium and the pregnancy outcome of in vitro fertilization-embryo transfer (IVF-ET) on the day of hCG injection. Methods: on the day of hCG injection, the maximum thickness of endometrium, the thickness of upper segment (10 mm from the fundus), the thickness of middle segment (20 mm from the fundus) and the difference between upper and middle segment (ETD,) were measured by transvaginal ultrasound in 256 patients who were treated with IVF-ET for the first time. That is, the upper segment thickness-middle section thickness). According to ETD, the patients were divided into four groups: group A (ETD0 mm); B group) (ETD 0. 0 mm); C group) (ETD 2. 1 + 4. 0 mm);). Group D (ETD4.0 mm),) was divided into two subgroups according to the age of 35 years: 鈮，

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