浙江省2010-2014年HIV感染孕产妇疫情及预防艾滋病母婴传播服务利用情况分析

发布时间：2018-11-10 09:49

【摘要】：目的了解浙江省2010-2014年艾滋病病毒(HIV)感染孕产妇疫情特征及预防艾滋病母婴传播(PMTCT)服务利用情况,为干预措施制定提供依据。方法通过收集整理2010-2014年浙江省预防艾滋病母婴传播工作报表和网络直报信息系统个案,采用构成比分析感染孕产妇人口学特征及服务利用情况,并采用趋势卡方检验比较相关指标的时间变化趋势。结果 2010-2014年,浙江省累计接受HIV抗体检测孕产妇总数3 311 646例,报告HIV感染孕产妇699例,孕产妇HIV抗体阳性检出率0.02%。2010-2014年,接受HIV抗体检测产妇比例逐年上升,2014年近100%。感染孕产妇以外省户籍、无固定职业、初中和小学以下文化程度为主。累计分娩产妇322例,占46.07%。分娩产妇中既往确诊87例(27.02%)、孕早期确诊32例(9.94%)、孕中期确诊55例(17.08%)、孕晚期确诊117例(36.33%)、产时确诊31例(9.63%)。不同年份,感染产妇及分娩儿童抗病毒用药构成比例差异有统计学意义(χ2产妇=44.38,P0.01;χ2婴儿=40.98,P0.01),均未呈现时间变化趋势。累计满18月龄儿童130例,接受HIV抗体检测76例,检测阳性2例,18月龄母婴传播率2.63%。结论 2010-2014年,浙江省孕产妇HIV感染率较低,人口学特征相对稳定,孕产妇接受HIV咨询、检测及感染产妇及其分娩儿童抗病毒治疗有较大提升,母婴传播率处于较低水平。但是,感染产妇孕早期确诊比例及抗病毒治疗指标仍有较大提升空间。
[Abstract]:Objective to investigate the epidemic characteristics of (HIV) infection in pregnant women in Zhejiang province from 2010 to 2014 and the utilization of (PMTCT) service for prevention of mother-to-child transmission of HIV, so as to provide the basis for the formulation of intervention measures. Methods by collecting and sorting out the information system of prevention of mother-to-child transmission of AIDS in Zhejiang Province from 2010 to 2014, the demographic characteristics of infected pregnant women and the utilization of services were analyzed by component ratio. The trend chi-square test was used to compare the time trends of related indicators. Results from 2010 to 2014, the total number of pregnant women who received HIV antibody detection in Zhejiang Province was 3 311,646, 699 women with HIV infection were reported. The positive detection rate of HIV antibody in pregnant women and pregnant women was 0.02. 2010-2014. The proportion of pregnant women tested with HIV antibody increased year by year. 2014 is close to 100. Infected pregnant and lying-in women with provincial household registration, no fixed occupation, junior high school and primary school below the level of education. The total number of parturients was 322, accounting for 46.07. 87 cases (27.02%) were diagnosed in the past, 32 cases (9.94%) in the early pregnancy, 55 cases (17.08%) in the second trimester, 117 cases (36.33%) in the third trimester and 31 cases (9.63%) at the time of delivery. In different years, there were significant differences in the proportion of antiviral drugs used in infected women and delivery children (蠂 ~ 2 = 44.38 P 0.01; 蠂 ~ 2 infants = 40.98 P 0.01), and there was no trend of time change. Of the 130 children aged 18 months, 76 were tested for HIV antibody, 2 were positive, and the mother-to-child transmission rate of 18 months was 2.63. Conclusion from 2010 to 2014, the HIV infection rate of pregnant and lying-in women in Zhejiang Province is relatively low, and the demographic characteristics are relatively stable. The pregnant and lying-in women receiving HIV counseling, testing and antiviral treatment of infected women and their children giving birth have been greatly improved, and the rate of mother-to-child transmission is at a low level. However, there is still room for improvement in the proportion of early pregnancy diagnosis and antiviral therapy in infected women.
【作者单位】：杭州市妇幼保健院保健部;浙江大学医学院附属妇产科医院保健部;浙江省卫生计生委妇幼健康服务处;
【基金】：浙江省教育厅科研项目(Y201224985)
【分类号】：R714.251

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