HIFU治疗不同T2WI信号强度的宫颈肌瘤的临床观察

发布时间：2018-11-14 13:15

【摘要】：目的评价高强度聚焦超声(HIFU)治疗磁共振上不同T2加权相(T2WI)信号强度的宫颈肌瘤的有效性及安全性。方法 23例行HIFU治疗的单发性宫颈肌瘤,根据磁共振图像中肌瘤与子宫正常肌层T2WI信号强度的对比,分为T2WI低信号组和T2WI高信号组,分析及比较其治疗剂量参数、消融率、治疗中副反应及治疗后并发症情况。结果治疗平均体积消融率为(73.12±15.29)%,T2WI低信号组平均体积消融率为(76.63±10.69)%,T2WI高信号组平均体积消融率为(62.96±16.85)%,二者有显著统计学差异(P0.05);T2WI高信号组治疗时间大于低信号组(P0.01),T2WI高信号组治疗能效因子大于低信号组(P0.05);治疗后无严重并发症发生。结论 HIFU治疗宫颈肌瘤安全可行;T2WI低信号的宫颈肌瘤治疗效果及治疗效率均明显高于高信号肌瘤,因而更适宜HIFU治疗。
[Abstract]:Objective to evaluate the efficacy and safety of high intensity focused ultrasound (HIFU) in the treatment of cervical leiomyoma with different T 2 weighted (T2WI) signal intensity on MRI. Methods 23 cases of single cervical myoma treated with HIFU were divided into T2WI low signal group and T2WI high signal group according to the contrast of T2WI signal intensity between myoma and normal myometrium in MRI image. The therapeutic dose parameters and ablation rate were analyzed and compared. Side effects and complications after treatment. Results the average volume ablation rate was (73.12 卤15.29)% in the treatment group, (76.63 卤10.69)% in the T2WI low signal group and (62.96 卤16.85)% in the high signal T2WI group. There was significant difference between them (P0.05). The treatment time of T2WI high signal group was longer than that of low signal group (P0.01), and the treatment energy efficiency factor of T2WI high signal group was larger than that of low signal group (P0.05). Conclusion HIFU is safe and feasible in the treatment of cervical leiomyoma, and the effect and efficiency of low signal T2WI in treating cervical myoma are obviously higher than that of high signal myoma, so it is more suitable for HIFU to treat cervical leiomyoma.
【作者单位】：重庆医科大学生物医学工程学院省部共建国家重点实验室培育基地-重庆市超声医学工程重点实验室重庆市生物医学工程学重点实验室;
【基金】：国家重点基础研究发展计划(973计划)项目(No.2011CB707900) 国家“十二五”科技支撑计划课题项目(No.2011BAI14B01) 国家重大科研仪器设备研制专项(No.81127901)
【分类号】：R737.33

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