漯河市机会性筛查近3年HPV亚型感染特征及趋势分析

发布时间：2018-11-18 22:13

【摘要】：目的探讨漯河市妇女近3年HPV亚型感染特征及趋势。方法回顾性分析2014年1月-2016年8月我院妇产科门诊参加宫颈HPV分型检测的18 994例女性患者,分析感染情况及3年来感染趋势。结果 18 994例患者中,HPV感染率为22.5%,前5感染亚型分别为HPV16(5.3%),HPV52(3.5%),HPV58(2.9%),HPV53(2.6%),HPV39(2.1%);不同年龄组别中,15-25岁组(32.9%)和56-60岁组(29.7%)感染率较高;单纯高危亚型感染率为83.1%,高于单纯低危亚型感染(9.2%)及高+低危亚型感染(7.7%);一重感染率占74.6%,高于多重感染(25.4%)。2014、2015、2016年HPV总感染率分别为25.1%(1 531/6 093)、22.1%(1 794/8 128)、19.7%(944/4773),呈下降趋势。结论漯河地区妇产科门诊就诊患者中,15-25岁组和56-60岁组患者HPV感染率高,且以一重感染和高危感染为主,感染亚型以16、52、58较为常见;近三年漯河地区妇产科门诊HPV感染有下降趋势。
[Abstract]:Objective to investigate the characteristics and trend of HPV subtype infection in Luohe women in recent three years. Methods from January 2014 to August 2016, 18 994 women who participated in cervical HPV typing were analyzed retrospectively. The infection status and infection trend in the past 3 years were analyzed. Results the infection rate of HPV in 18 994 patients was 22. 5%. The first 5 infection subtypes were HPV16 (5. 3%), HPV52 (3. 5%), HPV58 (2. 9%), HPV53 (2. 6%) and HPV39 (2. 1%). Among the different age groups, the infection rate was higher in 15-25 years old group (32.9%) and 56-60 years old group (29.7%). The infection rate of high risk subtype was 83.1%, which was higher than that of low risk subtype infection (9.2%) and high risk subtype infection (7.7%). The primary infection rate was 74.6%, higher than that of multiple infection rate (25.4%). The total infection rate of HPV in 2016 was 25.1% (1,531 / 6 093), 22.1% (1794 / 8,128) and 19.7% (944 / 4773), respectively. Conclusion among the outpatients in Luohe area, the infection rate of HPV in the 15-25 and 56-60 age groups is high, and the primary infection and high risk infection are mainly in the primary infection and the high risk infection. In recent three years, HPV infection in outpatient department of gynecology and obstetrics in Luohe area has a downward trend.
【作者单位】：漯河市中心医院妇产科/漯河医学高等专科学校第一附属医院妇产科;漯河医学高等专科学校药理教研室;
【基金】：漯河市青年拔尖人才科研项目(无编号) 河南省高等学校重点科研项目(17B320011) 漯河医学高等专科学校校级研究资助计划项目(2016-S-LMC-11) 河南省科技惠民计划项目(142207310008);稿号:201702402
【分类号】：R737.33

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