早发型子痫前期期待治疗对围生儿结局影响因素分析

发布时间：2018-11-21 09:55

【摘要】：目的探讨早发型子痫前期期待治疗的适宜时间及终止妊娠时机。方法回顾性分析自2012年4月至2014年4月在首都医科大学附属北京潞河医院治疗的65例早发型子痫前期患者的发病情况及妊娠结局,将65例患者根据发病孕周分为A、B两组。28~31~(+6)周的38例为A组(58.5%,28/65),32~34周的27例为B组(41.5%,27/65)。结果 A、B两组患者发病年龄、自觉症状、妊娠延长天数差异有统计学意义(P=0.000、P=0.028、P=0.000)。A、B组并发HELLP(hemolysis,elevated liver enzymes,and low platelet syndrome,HELLP)综合征及胎儿生长受限(fetal growth restriction,FGR)的发生率差异有统计学意义(P=0.045、P=0.000)。A、B组分娩孕周、出生体质量差异有统计学意义(P=0.000,P=0.043)。结论早发型子痫前期围生儿结局与分娩孕周、出生体质量、孕妇发病的孕周密切相关,发病越早,病情越严重,围生儿合并症的发病率越高。尽早干预治疗,严密观察母婴安危,个性化的选择适宜的分娩孕周,可获得最佳的母婴结局。
[Abstract]:Objective to explore the appropriate time and the time of termination of pregnancy for early-onset preeclampsia. Methods from April 2012 to April 2014, 65 early onset preeclampsia patients treated in Beijing Luhe Hospital of Capital Medical University were analyzed retrospectively. In group B, 38 cases were in group A (58.5%) and 27 cases in group B (41.5 / 27 / 65) at 31-6 weeks. Results there were significant differences in onset age, conscious symptoms and pregnancy prolongation days between the two groups (P = 0.000, P = 0.028, P = 0.000), while HELLP (hemolysis,elevated liver enzymes,and low platelet syndrome,) was found in group A (P = 0.000). There were significant differences in the incidence of HELLP syndrome and fetal growth restriction (fetal growth restriction,FGR) (P0.045 and P0. 000), and the difference of birth weight in group B was statistically significant (P0. 000 / P0. 043). Conclusion the early preeclampsia perinatal outcome is closely related to the gestational weeks, birth weight and gestational weeks of pregnancy. The earlier the preeclampsia occurs, the more serious the condition is, and the higher the incidence of perinatal complications is. Early intervention and treatment, strict observation of the safety of mother and child, individualized choice of appropriate delivery weeks, can obtain the best outcome of mother and child.
【作者单位】：首都医科大学附属北京潞河医院产科;
【分类号】：R714.244

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