马拉维360例艾滋病孕产妇母婴传播的干预措施及效果分析
发布时间：2018-11-22 08:02
【摘要】：目的分析马拉维对艾滋病孕产妇母婴传播干预措施的现状及效果。方法选择2012年3月至2013年5月确诊的360例艾滋病病毒(HIV)感染孕产妇,从规范使用抗反转录病毒(ART)药物、分娩方式和喂养方式三方面来干预,并对360例HIV感染孕产妇及其分娩的婴幼儿的HIV感染状态定期追踪随访。结果规范应用ART药物者,其母婴传播率为5.31%(17/320),同国内相仿,低于不规范服药者和未服药者的母婴传播率15.00%,两者差异有统计学意义(χ2=4.08,P0.05)。分娩方式中,剖宫产(急诊剖宫产和择期剖宫产)的母婴传播率为4.76%(4/84),略低于阴道分娩母婴传播率5.07%(14/276),两者差异无统计学意义(χ2=0.03,P0.05)。在规范使用ART药物及安全分娩前提下,母乳喂养的母婴传播率为14.71%(40/272),人工喂养的母婴传播率为4.17%(2/48),两者差异有统计学意义(χ2=3.97,P0.05)。规范应用ART药物和人工喂养的孕产妇,其艾滋病母婴传播率为4.17%(2/48),与未采取任何预防措施的艾滋病母婴传播率21.43%(3/14)相比,母婴传播率下降了80.54%。结论提早发现,规范用药、安全分娩及人工喂养,综合预防艾滋病母婴传播,才能有效降低艾滋病母婴传播水平。
[Abstract]:Objective to analyze the current situation and effect of HIV / AIDS mother-to-child transmission intervention in Malawi. Methods from March 2012 to May 2013, 360 pregnant women with HIV (HIV) infection were selected to intervene in three aspects: standard use of antiretroviral (ART) drugs, delivery mode and feeding mode. The HIV infection status of 360 pregnant women with HIV infection and their infants were followed up regularly. Results the rate of mother-to-child transmission of ART was 5.31% (17 / 320), which was similar to that in China, and was lower than that of non-standard and non-standard drug users (15.00%). The difference between them was statistically significant (蠂 ~ 2 / 4. 08, P < 0.05). P0.05). The mother-to-child transmission rate of cesarean section (emergency cesarean section and elective cesarean section) was 4.76% (4 / 84), slightly lower than that of vaginal delivery 5.07% (14 / 276). P0.05). The mother-to-child transmission rate of breast feeding was 14.71% (40 / 272) and that of artificial feeding was 4.17% (2 / 48) under the premise of standardized use of ART drugs and safe delivery. P0.05). The rate of mother-to-child transmission of HIV was 4.17% (2 / 48) for pregnant women who standardized the use of ART drugs and artificial feeding, compared with 21.43% (3 / 14) for mother-to-child transmission of HIV without any preventive measures. The rate of mother-to-child transmission decreased by 80.54. Conclusion early detection, standardized drug use, safe delivery and artificial feeding, comprehensive prevention of mother-to-child transmission of AIDS, can effectively reduce the level of mother-to-child transmission of AIDS.
【作者单位】： 宝鸡市人民医院;西安医学院附属医院;榆林市第二医院;Mzuzu
【基金】：陕西省教育厅基金(12JK0767)~~
【分类号】：R714.251
本文编号：2348614
[Abstract]:Objective to analyze the current situation and effect of HIV / AIDS mother-to-child transmission intervention in Malawi. Methods from March 2012 to May 2013, 360 pregnant women with HIV (HIV) infection were selected to intervene in three aspects: standard use of antiretroviral (ART) drugs, delivery mode and feeding mode. The HIV infection status of 360 pregnant women with HIV infection and their infants were followed up regularly. Results the rate of mother-to-child transmission of ART was 5.31% (17 / 320), which was similar to that in China, and was lower than that of non-standard and non-standard drug users (15.00%). The difference between them was statistically significant (蠂 ~ 2 / 4. 08, P < 0.05). P0.05). The mother-to-child transmission rate of cesarean section (emergency cesarean section and elective cesarean section) was 4.76% (4 / 84), slightly lower than that of vaginal delivery 5.07% (14 / 276). P0.05). The mother-to-child transmission rate of breast feeding was 14.71% (40 / 272) and that of artificial feeding was 4.17% (2 / 48) under the premise of standardized use of ART drugs and safe delivery. P0.05). The rate of mother-to-child transmission of HIV was 4.17% (2 / 48) for pregnant women who standardized the use of ART drugs and artificial feeding, compared with 21.43% (3 / 14) for mother-to-child transmission of HIV without any preventive measures. The rate of mother-to-child transmission decreased by 80.54. Conclusion early detection, standardized drug use, safe delivery and artificial feeding, comprehensive prevention of mother-to-child transmission of AIDS, can effectively reduce the level of mother-to-child transmission of AIDS.
【作者单位】： 宝鸡市人民医院;西安医学院附属医院;榆林市第二医院;Mzuzu
【基金】：陕西省教育厅基金(12JK0767)~~
【分类号】：R714.251
【共引文献】
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