完全性葡萄胎与正常胎儿共存4例报告并文献复习

发布时间：2018-11-29 10:28

【摘要】：目的探讨完全性葡萄胎与正常胎儿共存(CHMCF)的临床特点、诊断方法、妊娠结局及预后。方法收集并分析广州医科大学附属广东省妇幼保健院2013年1月1日至发稿时4例经临床及病理证实为CHMCF病例的临床资料,并回顾分析相关文献。结果 1例体外受精-胚胎移植(IVF-ET)后获得妊娠。3例因阴道流血不适就诊,其中2例因阴道流血而终止妊娠;2例合并甲状腺功能亢进;1例并发妊娠期高血压疾病;1例胎死宫内。4例清宫前h CG均大于100kU/L。3例在终止妊娠前超声提示CHMCF。3例合并妊娠滋养细胞肿瘤。结论 CHMCF患者是否继续妊娠可根据产前诊断中胎儿染色体是否正常及妊娠期间是否出现危害母婴健康的合并症和并发症做进一步判断。若以上情况均无发生,可在严密观察下继续妊娠直至分娩;反之应适时终止妊娠。
[Abstract]:Objective to investigate the clinical features, diagnostic methods, pregnancy outcome and prognosis of complete hydatidiform mole coexisting with normal fetus. Methods the clinical data of 4 cases of CHMCF confirmed clinically and pathologically by Guangdong Maternal and Child Health Institute affiliated to Guangzhou Medical University from January 1, 2013 to publication were analyzed retrospectively. Results pregnancy was obtained in 1 case after in vitro fertilization and embryo transfer (IVF-ET), 3 cases were treated for vaginal bleeding discomfort, 2 cases were terminated due to vaginal bleeding, 2 cases were complicated with hyperthyroidism, 1 case was complicated with hypertension complicating pregnancy, 2 cases were complicated with hyperthyroidism and 1 case was complicated with hypertension complicating pregnancy. In 1 case of fetal death, the CG in 4 cases was higher than that in 100kU/L.3 before pregnancy. In 4 cases, CHMCF.3 was associated with gestational trophoblastic tumor before termination of pregnancy. Conclusion further judgment can be made on the basis of whether the fetal chromosome is normal in prenatal diagnosis and whether complications and complications are harmful to the health of mother and child during pregnancy in patients with CHMCF. If none of the above occurs, you can continue pregnancy until delivery under close observation; conversely, termination of pregnancy should be timely.
【作者单位】：广州医科大学附属广东省妇幼保健院妇科;
【基金】：广州市科技和信息化局项目(201510010173)
【分类号】：R737.33

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