宫颈环形电切术不同宫颈切除深度对宫颈上皮内瘤变患者宫颈机能及生存质量的影响

发布时间：2018-12-12 02:53

【摘要】：目的评价宫颈环形电切术(LEEP)不同宫颈切除深度对宫颈上皮内瘤变患者宫颈机能及生存质量的影响。方法将408例行LEEP的宫颈上皮内瘤变(CIN)患者随机分为观察组和对照组各204例,两组术中宫颈切除深度分别为15~20 mm和21~25 mm。比较两组近期疗效及随访结果。结果观察组术中出血量、手术时间、CIN级别变化、治愈率、术后出血、术后感染情况与对照组比较均无统计学差异(P均0.05)。术后3个月,观察组宫颈修复情况均明显优于对照组,宫颈狭窄程度亦较对照组减轻(P均0.05)。术后1年,观察组宫颈裂伤、宫颈机能不全的发生率明显低于对照组(P均0.05)。术后观察组生存质量各项评分皆高于对照组(P0.05或0.01)。结论 LEEP术中宫颈切除深度对女性术后宫颈修复及宫颈狭窄、宫颈裂伤、宫颈机能不全的发生影响较大。
[Abstract]:Objective to evaluate the effect of different depth of cervical excision (LEEP) on cervical function and quality of life (QOL) in patients with cervical intraepithelial neoplasia. Methods 408 LEEP patients with cervical intraepithelial neoplasia (CIN) were randomly divided into observation group (n = 204) and control group (n = 204). The depth of cervical excision during operation was 1520 mm and 2125 mm., respectively. The short-term curative effect and follow-up results were compared between the two groups. Results there was no significant difference in intraoperative bleeding, operative time, CIN grade, cure rate, postoperative bleeding and postoperative infection between the observation group and the control group (P < 0. 05). 3 months after operation, the cervical repair in the observation group was significantly better than that in the control group, and the degree of cervical stricture in the observation group was less than that in the control group (P 0.05). 1 year after operation, the incidence of cervical laceration and cervical dysfunction in the observation group was significantly lower than that in the control group (P 0.05). The quality of life scores in the observation group were higher than those in the control group (P0.05 or 0.01). Conclusion the depth of cervical excision during LEEP has great influence on the occurrence of cervical repair, cervical stricture, cervical laceration and cervical insufficiency in women after operation.
【作者单位】：广东省妇幼保健院;
【分类号】：R737.33

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