妊娠期高血压的危险因素

发布时间：2019-01-11 20:11

【摘要】：目的探讨妊娠期高血压的危险因素,为预防妊娠期高血压发病提供参考依据。方法采用1∶2配对病例对照研究方法,入选2010年3月至2013年3月福建医科大学附属第一医院住院分娩的妊娠期高血压患者372例(病例组)和同期足月分娩健康新生儿的非妊娠期高血压者744名(对照组)作为研究对象。采用问卷调查和查阅临床资料相结合的方式,收集两组的基础资料,并对危险因素进行单因素和多因素非条件Logistic回归分析。结果与对照组相比,病例组年龄较大;24h尿白蛋白含量、血肌酐水平较高;孕前体质量指数(BMI)≥24kg/m2、糖化血红蛋白(HbA1c)在6.0%~6.5%、孕妇情绪焦虑和妊娠≥2胎者所占的比例较高;孕期检查≥6次所占的比例较低(均P0.05)。单因素Logistic回归分析显示:年龄、孕前BMI、HbA1c、24h尿白蛋白含量、血肌酐水平、孕期检查次数、孕妇情绪、多胎妊娠是妊娠期高血压的危险因素(均P0.05)。多因素非条件Logistic显示:年龄(OR=1.317)、孕前BMI(OR=1.183)、HbA1c(OR=1.303)、24h尿白蛋白(OR=2.847)、血肌酐(OR=1.102)是妊娠期高血压发生的独立危险因素。结论年龄较大、孕前BMI≥24kg/m2、HbA1c在6.0%~6.5%、24h尿白蛋白含量和血肌酐水平较高的孕妇,容易发生妊娠期高血压。
[Abstract]:Objective to explore the risk factors of hypertension complicating pregnancy and to provide reference for the prevention of hypertension complicating pregnancy. Methods the 1:2 matched case-control study was used. From March 2010 to March 2013, 372 cases of hypertensive complicating pregnancy (case group) and 744 cases of non-gestational hypertension (control group) were enrolled in the first affiliated Hospital of Fujian Medical University. ) as the object of study. The basic data of the two groups were collected by means of questionnaire and consulting clinical data, and univariate and multivariate unconditional Logistic regression analysis were used to analyze the risk factors. Results compared with the control group, the age of the case group was older, and the urinary albumin content and creatinine level were higher in the 24 h urinary albumin group than in the control group. The pregestational body mass index (BMI) 鈮，

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