高危型HPV联合液基细胞检测在宫颈癌筛查中的临床价值

发布时间：2019-01-23 16:32

【摘要】：目的分析新柏压液基细胞学技术分析(TCT)联合高危型HPV病毒筛查在临床宫颈癌筛查中的应用价值。方法选择2014年1月至2015年12月期间于本院接受宫颈癌筛查的300例女性为研究对象,分别采用阴道镜下宫颈组织病理活检、TCT检查及高危型HPV病毒筛查以及后二者联合检查的方法,以病理活检结果为检查"金标准",计算TCT检查与高危型HPV病毒筛查以及二者联用诊断结果的准确性、灵敏度和特异性。结果对照病理活检结果发现,单用TCT检查准确性、灵敏度、特异性分别为80.00%、74.80%、83.82%、单用高危型HPV病毒筛查结果准确性、灵敏度、特异性分别为75.67%、87.40%、67.05%,二者联用与病理结果相比检查准确性、灵敏度、特异性分别为99.67%、99.21%、100.00%,差异显著,具有统计学意义,P0.05。结论相比单用TCT检查、高危型HPV病毒筛查,二者联用在宫颈癌的筛查中显著提高宫颈癌筛查的准确性、灵敏性与特异性,显著提高临床确诊率,临床具有较高的应用价值。
[Abstract]:Objective to analyze the application value of (TCT) combined with high risk HPV virus screening in clinical cervical cancer screening. Methods 300 women who were screened for cervical cancer from January 2014 to December 2015 were selected as study subjects, and pathological biopsy of cervical tissue was performed under colposcopy. The methods of TCT examination, high risk HPV virus screening and combined examination of the latter two were used to calculate the accuracy of TCT examination and high risk HPV virus screening, and the accuracy of the diagnostic results combined with the results of pathological biopsy as the "golden standard". Sensitivity and specificity. Results compared with pathological biopsy results, the accuracy, sensitivity and specificity of TCT alone were 84.80 and 83.82, respectively. The specificity was 75.677.40 and 67.05, respectively. The accuracy, sensitivity and specificity of the two methods were 99.677.21 and 100.000.The differences were significant and statistically significant. P0.05. Conclusion compared with TCT alone, high risk HPV virus screening can significantly improve the accuracy, sensitivity and specificity of cervical cancer screening, and improve the rate of clinical diagnosis.
【作者单位】：东莞市妇幼保健院;
【分类号】：R737.33

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