女性不孕症患者细菌性阴道病与支原体感染状况分析

发布时间：2019-04-16 16:55

【摘要】：目的调查女性不孕症患者细菌性阴道病(BV)与支原体感染状况。方法收集2013年6-12月在海南省人民医院妇科门诊就诊的541例女性不孕症患者分泌物标本,同时做BV检测和支原体培养及药敏试验。结果支原体培养阳性率为44.5%(241/541),其中解脲支原体(UU)检出率最高,有223例感染,阳性率41.2%,人型支原体(Mh)感染5例,阳性率0.9%,UU+Mh混合阳性13例,阳性率2.4%。BV感染325例,阳性率为60.1%(325/541)。在241例支原体阳性患者中BV阳性检出率为70.1%(169/241),300例支原体阴性患者中BV阳性检出率为52.0%(156/300),支原体阳性组与支原体阴性组BV的检出率比较,差异有统计学意义(P0.05)。氟诺喹类的氧氟沙星耐药率最高,敏感率只有7.1%。交沙霉素耐药率最低,占3.7%。结论女性不孕症患者与BV和支原体感染密切相关,应加强BV及支原体普查,做到早诊断,早治疗。支原体药敏试验显示,强力霉素、美满霉素、交沙霉素敏感率最高,可以作为临床医生首选药物。
[Abstract]:Objective to investigate the (BV) and mycoplasma infection in female infertility patients with bacterial vaginosis. Methods the secretions of 541 female infertile patients were collected from June to December 2013 in the department of gynaecology of Hainan Provincial people's Hospital. BV test, mycoplasma culture and drug sensitivity test were performed at the same time. Results the positive rate of mycoplasma culture was 44.5% (241 ~ 541), among which Ureaplasma Urealyticum (UU) was the highest (41.2%), Mycoplasma hominis (Mh) infection was found in 5 patients (0.9%), and Ureaplasma Urealyticum infection was the highest (41.2%). The positive rate of UU Mh was 60.1% (325 / 541), and the positive rate of 2.4%.BV infection was 60.1% (325 / 541). The positive rate of BV was 70.1% (169 / 241) in mycoplasma positive group and 52.0% (156 / 300) in mycoplasma negative group. The positive rate of BV in mycoplasma positive group and mycoplasma negative group was 52.0% (156 / 300), and 52.0% (156 / 300) in mycoplasma positive group and mycoplasma negative group, respectively. The difference was statistically significant (P0.05). The resistance rate of ofloxacin to fluoroquine was the highest, and the sensitive rate was only 7.1%. The drug resistance rate of Jiaoshamycin was the lowest, accounting for 3.7%. Conclusion female infertility patients are closely related to BV and mycoplasma infection. It is necessary to strengthen BV and mycoplasma screening to make early diagnosis and treatment. Mycoplasma susceptibility test showed that doxycycline, methamphenicol and josamycin had the highest susceptibility rate and could be used as the first choice for clinicians.
【作者单位】：海南省人民医院检验科;海南省皮肤性病防治中心;
【分类号】：R711.6

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