DSA介导下输卵管近端梗阻介入再通术联合IUI治疗不孕症的临床研究

发布时间：2019-04-22 10:40

【摘要】：目的:探讨数字减影血管造影机(DSA)介导下输卵管近端梗阻介入再通术联合夫精宫腔内人工授精(IUI)的临床效果。方法:2010年1月至2012年12月输卵管近端梗阻介入再通术成功后接受IUI治疗的191例不孕患者为观察组,取同期无输卵管近端梗阻行IUI的746例患者为对照组,对两组的临床资料进行分析。结果:观察组临床妊娠率(30.37%)与对照组(27.75%)相比较,差异无统计学意义(P0.05);各不同IUI原因组内观察组临床妊娠率与对照组相比较,差异均无统计学意义(P0.05)。在观察组中,4个IUI原因组间临床妊娠率相比较,差异有统计学意义(P0.05);行组间卡方分割后,男性因素及宫颈因素组临床妊娠率高于其他两组(P0.01)。在对照组中,4个IUI原因组间临床妊娠率相比较,差异有统计学意义(P0.01);行组间卡方分割后,男性因素组及宫颈因素组临床妊娠率高于其他两组(P0.01)。结论:DSA介导下输卵管近端梗阻介入再通术联合IUI的临床效果良好,不同IUI原因中男性因素及宫颈因素患者的临床妊娠率高于其他因素的患者。
[Abstract]:Aim: to investigate the clinical effect of interventional recanalization of proximal tubal obstruction mediated by digital subtraction angiography (DSA) combined with artificial insemination (IUI). Methods: from January 2010 to December 2012, a total of 191 infertile patients who received IUI after successful interventional recanalization of proximal fallopian tube obstruction were selected as the observation group, and 746 patients without obstruction of the proximal fallopian tube during the same period were selected as the control group. The clinical data of the two groups were analyzed. Results: the clinical pregnancy rate in the observation group (30.37%) was not significantly different from that in the control group (27.75%) (P0.05). There was no significant difference in the clinical pregnancy rate between the observation group and the control group in the different IUI reasons group (P0.05). In the observation group, the clinical pregnancy rate of the four IUI causes group was significantly higher than that of the other two groups (P0.05), and the clinical pregnancy rate of the male factor and cervical factor group was higher than that of the other two groups (P0.01). In the control group, there was a significant difference in the clinical pregnancy rates among the four IUI causes groups (P0.01), and the clinical pregnancy rates in the male factor group and cervical factor group were higher than those in the other two groups (P0.01). Conclusion: DSA-mediated interventional recanalization of proximal fallopian tube obstruction combined with IUI has a good clinical effect. The clinical pregnancy rate of male and cervical factors in different IUI causes is higher than that of other factors.
【作者单位】：汕头大学医学院第一附属医院;广州医科大学附属第三医院;
【分类号】：R711.6

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