黄体血流分级对未破裂型输卵管妊娠保守治疗的影响
发布时间：2019-04-23 15:35
【摘要】：目的:研究黄体血流分级对于未破裂型输卵管妊娠保守治疗的影响,为患者临床治疗提供参考。方法:回顾性分析2013年6月至2016年12月在西安交通大学第一附属医院妇产科就诊的未破裂型输卵管妊娠保守治疗132例患者的临床资料,根据妊娠黄体的血流分级分为0级组(31例)、1级组(34例)、2级组(38例)、3级组(29例)。比较各组患者治疗后血β-人绒毛膜促性腺激素(β-HCG)下降、包块缩小情况及疗效。结果:(1)黄体血流分级中0级组患者治疗后不同时间点血β-HCG水平均最低、下降至正常所需时间最短(14.39±2.67天),保守治疗后不同时间点包块直径均最小,包块完全消失所需时间最短(13.30±2.24天);3级组患者血β-HCG水平均最高,下降至正常所需时间最长(27.04±4.56天),保守治疗后不同时间点包块直径均最大,包块完全消失所需时间最长(24.11±3.44天),4组间比较,差异有统计学意义(P0.05)。(2)黄体血流分级中0级组患者治疗有效率最高(90.32%),3级组最低(72.41%),4组间比较,差异有统计学意义(P0.05)。(3)所有患者中不良反应包括血清转氨酶升高5例、胃肠道反应9例、困乏嗜睡4例,4组间不良反应比较经Fisher确切概率法检验,差异无统计学意义(P0.05),保守治疗结束后患者不良反应均消失。结论:黄体血流分级对未破裂型输卵管妊娠保守治疗有影响,血流分级越高,治疗所需时间越长,疗效越差。
[Abstract]:Objective: to study the effect of luteal blood flow grading on conservative treatment of unruptured tubal pregnancy. Methods: the clinical data of 132 cases of unruptured tubal pregnancy treated conservatively from June 2013 to December 2016 in the department of gynaecology and obstetrics of the first affiliated Hospital of Xi'an Jiaotong University were retrospectively analyzed. According to the blood flow grade of corpus luteum, they were divided into three groups: grade 0 (n = 31), grade 1 (n = 34), grade 2 (n = 38) and grade 3 (n = 29). The serum 尾-human chorionic gonadotropin (尾-HCG), mass reduction and curative effect were compared in each group after treatment. Results: (1) the level of 尾-HCG in group 0 was the lowest at different time points after treatment, and the shortest time was required to decrease to normal (14.39 卤2.67 days), and the diameter of mass was the smallest at different time points after conservative treatment. It took the shortest time for the mass to disappear completely (13.30 卤2.24 days). The level of serum 尾-HCG was the highest in grade 3 patients, and the longest time was required to decrease to normal (27.04 卤4.56 days). The diameter of the masses was the largest at different time points after conservative treatment, and the longest time was required for the complete disappearance of the masses (24.11 卤3.44 days). 4 the difference between groups was statistically significant (P0.05). (2). The effective rate of treatment was the highest in grade 0 group (90.32%), the lowest in grade 3 group (72.41%), and among the four groups, the treatment efficiency was the highest in grade 0 group (90.32%), the lowest in grade 3 group (72.41%). The difference was statistically significant (P0.05). (3) in all patients, including elevated serum transaminase (5 cases), gastrointestinal reactions (9 cases) and sleepiness (4 cases). The adverse reactions among the 4 groups were tested by Fisher's exact probability method. There was no significant difference between the two groups (P0.05). The adverse reactions disappeared after conservative treatment. Conclusion: luteal blood flow grading has an effect on conservative treatment of unruptured tubal pregnancy. The higher the blood flow grade, the longer the treatment time and the worse the curative effect.
【作者单位】： 西安交通大学第一附属医院;
【分类号】：R714.221
本文编号：2463593
[Abstract]:Objective: to study the effect of luteal blood flow grading on conservative treatment of unruptured tubal pregnancy. Methods: the clinical data of 132 cases of unruptured tubal pregnancy treated conservatively from June 2013 to December 2016 in the department of gynaecology and obstetrics of the first affiliated Hospital of Xi'an Jiaotong University were retrospectively analyzed. According to the blood flow grade of corpus luteum, they were divided into three groups: grade 0 (n = 31), grade 1 (n = 34), grade 2 (n = 38) and grade 3 (n = 29). The serum 尾-human chorionic gonadotropin (尾-HCG), mass reduction and curative effect were compared in each group after treatment. Results: (1) the level of 尾-HCG in group 0 was the lowest at different time points after treatment, and the shortest time was required to decrease to normal (14.39 卤2.67 days), and the diameter of mass was the smallest at different time points after conservative treatment. It took the shortest time for the mass to disappear completely (13.30 卤2.24 days). The level of serum 尾-HCG was the highest in grade 3 patients, and the longest time was required to decrease to normal (27.04 卤4.56 days). The diameter of the masses was the largest at different time points after conservative treatment, and the longest time was required for the complete disappearance of the masses (24.11 卤3.44 days). 4 the difference between groups was statistically significant (P0.05). (2). The effective rate of treatment was the highest in grade 0 group (90.32%), the lowest in grade 3 group (72.41%), and among the four groups, the treatment efficiency was the highest in grade 0 group (90.32%), the lowest in grade 3 group (72.41%). The difference was statistically significant (P0.05). (3) in all patients, including elevated serum transaminase (5 cases), gastrointestinal reactions (9 cases) and sleepiness (4 cases). The adverse reactions among the 4 groups were tested by Fisher's exact probability method. There was no significant difference between the two groups (P0.05). The adverse reactions disappeared after conservative treatment. Conclusion: luteal blood flow grading has an effect on conservative treatment of unruptured tubal pregnancy. The higher the blood flow grade, the longer the treatment time and the worse the curative effect.
【作者单位】： 西安交通大学第一附属医院;
【分类号】：R714.221
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