两种抗菌药物在妇产科患者感染防治中的应用研究

发布时间：2019-04-23 14:12

【摘要】：目的分析头孢哌酮/舒巴坦及阿莫西林/克拉维酸在妇产科感染患者防治中的应用效果,为临床治疗提供参考。方法选取医院2011-2013年收治的426例妇产科感染患者,根据其用药不同分为观察组和对照组,观察组213例选用头孢哌酮/舒巴坦进行抗感染治疗,对照组213例选用阿莫西林/克拉维酸抗感染治疗,对比两组患者临床疗效及不良反应发生率。结果患者临床治疗总有效率观察组为96.2%、对照组为95.7%,差异无统计学意义;两组患者检出病原菌共387株,检出率为90.8%,病原菌清除率观察组为91.2%、对照组为89.7%,差异无统计学意义,同时两组患者不良反应发生率差异也无统计学意义。结论头孢哌酮/舒巴坦及阿莫西林/克拉维酸均可有效防治妇产科感染疾病,安全可靠值得临床推广应用。
[Abstract]:Objective to analyze the effect of cefoperazone / sulbactam and amoxicillin / clavulanic acid in the prevention and treatment of gynecological and obstetrical infection. Methods 426 patients with gynaecology and obstetrics infection in the hospital from 2011 to 2013 were divided into observation group and control group according to their drug use. 213 cases in observation group were treated with cefoperazone / sulbactam for anti-infection treatment. In the control group, 213 cases were treated with amoxicillin / clavulanic acid for anti-infective therapy, and the clinical efficacy and the incidence of adverse reactions were compared between the two groups. Results the total effective rate of clinical treatment was 96.2% in the observation group and 95.7% in the control group. There was no significant difference between the two groups. A total of 387 strains of pathogenic bacteria were detected in the two groups, the detection rate was 90.8%, the pathogen clearance rate was 91.2% in the observation group and 89.7% in the control group, there was no significant difference between the two groups. At the same time, there was no significant difference in the incidence of adverse reactions between the two groups. Conclusion Cefoperazone / sulbactam and amoxicillin / clavulanic acid can effectively prevent and cure gynecological and obstetrical infections, which is safe and reliable and worthy of clinical application.
【作者单位】：聊城市第三人民医院妇产科;
【基金】：山东省科技局科研基金资助项目(2006-060) 山东省聊城市科技局基金资助项目(2007卫-3-63-2-2)
【分类号】：R71

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