HIV阳性妇女感染高危型人乳头瘤病毒的临床研究

发布时间：2019-05-10 17:08

【摘要】：目的探讨妇女感染HIV(human immunodeficiency virus,HIV)与人乳头瘤状病毒(human papillomavirus,HPV)感染的相关性,为HIV/AIDS(acquired immunodeficiency syndrome,AIDS)妇女宫颈病变的早期发现及治疗提供线索和依据。方法将2011年6月至2012年5月在首都医科大学附属北京地坛医院妇科门诊进行筛查的53例HIV/AIDS妇女作为实验组,58例HIV阴性妇女作为对照组,同时进行TCT(thinprep cytologic test,TCT)及HPV(human papillomavirus,HPV)检测。结果 53例HIV/AIDS妇女TCT异常48例(90.56%,48/53),58例HIV阴性妇女中,TCT异常27例(46.55%,27/58),两组TCT异常概率差异有统计学意义(P0.05);53例HIV/AIDS妇女中高危型HPV 14例(26.41%,14/53);58例HIV阴性妇女高危型HPV高危型10例(17.24%,10/58),两组感染高危型HPV的概率差异无统计学意义(P0.05)。结论两组患者的TCT异常有差异,但高危型HPV感染没有差异。
[Abstract]:Objective to investigate the relationship between HIV (human immunodeficiency virus,HIV infection and human papillomavirus (human papillomavirus,HPV) infection in women, and to provide clues and evidence for early detection and treatment of cervical lesions in HIV/AIDS (acquired immunodeficiency syndrome,AIDS) women. Methods from June 2011 to May 2012, 53 HIV/AIDS women who were screened in the gynecological clinic of The Temple of Earth Hospital affiliated to Capital Medical University were selected as the experimental group and 58 HIV negative women as the control group. TCT (thinprep cytologic test, was also performed at the same time. TCT and HPV (human papillomavirus,HPV) detection. Results among 53 HIV/AIDS women, 48 (90.56%, 48 / 53) had abnormal TCT. Among 58 HIV negative women, 27 (46.55%, 27 / 58) had abnormal TCT. There was a significant difference in the abnormal probability of TCT between the two groups (P0.05). Among 53 HIV/AIDS women, 14 (26.41%) were high risk HPV and 10 (17.24%, 10 卤58) were high risk HPV in 58 HIV negative women. There was no significant difference in the probability of high risk HPV infection between the two groups (P 0.05). Conclusion there is difference in TCT abnormality between the two groups, but there is no difference in high risk HPV infection between the two groups.
【作者单位】：首都医科大学附属北京地坛医院妇产科;
【分类号】：R737.33

【相似文献】