不同时间给予米索前列醇防治二次剖宫产产后出血

发布时间：2019-05-17 06:11

【摘要】：目的:探索米索前列醇不同时间给药防治二次剖宫产患者产后出血的临床效果。方法:将入选的126例二次剖宫产孕妇按照入院先后编号,随机分为三组:缩宫素组(A组,42例),术中、术后常规应用缩宫素;术后米索前列醇组(B组,41例),在A组基础上术后直肠放置米索前列醇;术中米索前列醇组(C组,43例),在A组基础上术中含服米索前列醇。比较三组患者术中、术后0~2h、术后3~24h出血量,产后出血发生率及产后出血控制措施。结果:C组患者术中、术后0~2h、术后3~24h出血量分别为(240.12±64.09)ml、(51.26±15.04)ml、(61.26±19.80)ml,均比A组出血量少(P0.05);C组患者术中和术后0~2h出血量显著低于B组(P0.05);B组患者术后0~2h、术后3~24h出血量显著低于A组(P0.05)。C组患者产后出血发生率为4.65%,显著低于A组(23.81%)(P0.05)。A组采取增加药物止血措施的比例为19.05%,显著高于C组(2.33%)(P0.05)。结论:术中含服米索前列醇联合缩宫素防治二次剖宫产产后出血较术后给予米索前列醇和单纯缩宫素给药临床效果好。
[Abstract]:Objective: to explore the clinical effect of misoprostol in the prevention and treatment of postpartum hemorrhage in patients with secondary cesarean section. Methods: 126 pregnant women undergoing secondary cesarean section were randomly divided into three groups: oxytocin group (group A, n = 42). Misoprostol was placed in rectum in group A (n = 41) and misoprostol in group C (n = 43). The amount of bleeding, the incidence of postpartum hemorrhage and the control measures of postpartum hemorrhage were compared between the three groups during operation, 0 hours after operation and 3 hours after operation. Results: the bleeding volume of group C was (240.12 卤64.09) ml, (51.26 卤15.04) ml, (61.26 卤19.80) ml, which was less than that of group A (P 0.05). The amount of bleeding in group C was significantly lower than that in group B during and 2 hours after operation (P 0.05). The amount of bleeding in group B was significantly lower than that in group A at 0 h and 24 h after operation (P 0.05, the incidence of postpartum hemorrhage in). C group was 4.65%). It was significantly lower than that of group A (23.81%) (P 0.05). The proportion of increasing drug hemostatic measures in). A group was 19.05%, which was significantly higher than that in group C (2.33%) (P 0.05). Conclusion: the clinical effect of misoprostol combined with oxytocin in the prevention and treatment of postpartum hemorrhage after secondary cesarean section is better than that of misoprostol and oxytocin alone.
【作者单位】：新疆医科大学第一附属医院产科;
【分类号】：R719.8

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