基于CT数据的正常胎儿骨骼数字化三维重建模型的建立及价值

发布时间：2019-05-30 03:43

【摘要】：目的构建基于CT数据的正常胎儿骨骼数字化重建三维模型,对该方法在胎儿骨骼发育异常产前诊断中的应用价值进行初步探讨,为异常胎儿骨骼研究设立对照。方法对2例自愿参加研究的计划生育引产孕妇(1例妊娠26+2周,1例妊娠27+4周)产前行腹部CT扫描,利用CT自带软件(MIP法及VRT法)对胎儿骨骼进行重建,同时将Dicom原始二维断层图像数据集导入Mimics 10.01软件进行胎儿骨骼三维重建,观察胎儿骨骼情况,并对各种重建方法的重建效果进行初步比较。结果利用CT自带软件及Mimics 10.01软件重建获取的胎儿骨骼数字化模型均可清楚地显示胎儿骨骼情况,以VRT重建法及Mimics10.01软件重建模型的效果更佳,重建模型不仅可以任意比例缩放和任意角度旋转以显示骨骼间的毗邻关系和空间构象,且可对其进行任意径线和角度的精确测量。结论基于CT数据,利用VRT重建法及Mimics10.01软件均可方便快捷地建立出逼真清晰的胎儿骨骼数字化三维模型。对于超声检查不能明确诊断的骨骼发育异常胎儿,必要时可以辅以CT检查并对胎儿骨骼进行三维重建以进一步明确诊断。
[Abstract]:Objective to construct a three-dimensional model of digital reconstruction of normal fetal bone based on CT data, and to explore the application value of this method in antenatal diagnosis of abnormal fetal bone development, and to set up a control for the study of abnormal fetal bone. Methods abdominal CT scan was performed in 2 pregnant women who volunteered to participate in the study (1 case of 26 2 weeks gestation and 1 case of 27 4 weeks gestation). The fetal skeleton was reconstructed by CT software (MIP method and VRT method). At the same time, the original two-dimensional tomographic image data set of Dicom was imported into Mimics 10.01 software for three-dimensional reconstruction of fetal skeleton, the situation of fetal bone was observed, and the reconstruction effects of various reconstruction methods were compared. Results the digital model of fetal bone reconstructed by CT and Mimics10.01 software could clearly display the fetal bone, and the reconstruction of fetal bone by VRT reconstruction and Mimics10.01 software was more effective. The reconstruction model can not only scale and rotate at any angle to show the adjacent relationship and spatial conformational relationship between bones, but also measure the arbitrary diameter and angle accurately. Conclusion based on CT data, VRT reconstruction method and Mimics10.01 software can be used to establish realistic and clear three-dimensional digital model of fetal bone conveniently and quickly. For fetuses with abnormal bone development that can not be clearly diagnosed by ultrasound, CT examination and three-dimensional reconstruction of fetal bones can be supplemented if necessary to further make a definite diagnosis.
【作者单位】：新疆乌鲁木齐市水磨沟区人民医院妇产科;南方医科大学南方医院妇产科;
【基金】：国家自然科学基金资助项目(编号:31271417)
【分类号】：R714.5

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