二维超声联合STIC技术在胎儿先心病筛查中的应用

发布时间：2019-06-10 10:21

【摘要】：目的 心脏大血管结构发育畸形是一类较常见的胎儿先天性发育畸形，由于受多种因素影响，产前常规二维超声心动图检查对胎儿先天性心脏病的诊断有一定局限性，本课题旨在探讨二维超声心动图联合时间-空间关联成像(STIC)技术在胎儿先天性心脏病筛查中的应用价值。 方法 收集2011年9月~2013年5月在我院进行胎儿产前畸形筛查的孕妇11036例。用GE-Voluson E8仪器进行二维超声扫查及三维STIC成像，部分胎儿进行STIC容积数据库采集及脱机分析，并记录二维超声及STIC心脏扫描时间。先天性心脏病胎儿引产后进行尸体解剖或出生后随访结果对照。 结果 1.单纯二维超声心动图与二维超声联合STIC技术两种检查方法对95例胎儿先心病的诊断符合率(分别为95.79%、98.95%)比较，差异无统计学意义。 2.检出的先心病胎儿中，87例记录二维筛查时间，平均每个胎儿心脏用时(9.68±2.13)min，，每幅图像所用时间(1.03±0.80)min，79例记录STIC技术扫描时间，平均每次STIC扫描用时(7.76±2.42)min，每幅图像所用时间(0.78±0.56)min，对两种方法所得每例样本和每幅图像的时间进行比较，差异均有统计学意义(P0.05，P0.01)。 3.不同孕周二维超声心动图与STIC技术各重要切面显示合格率差异无统计学意义，随着孕龄增大，STIC技术对各重要切面显示合格率较二维超声的优势逐渐变小。 4.确诊为完全型大动脉转位的胎儿心脏根据是否合并室间隔缺损（VSD）及肺动脉狭窄（PAS），可将完全型大动脉转位分为三型，即单纯型大动脉转位、完全型大动脉转位伴室间隔缺损、完全型大动脉转位伴室间隔缺损及肺动脉狭窄。 结论 1.STIC技术较二维超声缩短了心脏检查时间，特别是有心脏发育畸形胎儿的胎心照射时间得到大大缩短。 2.二维超声联合STIC技术对胎儿先心病的检出率及诊断符合率均有所提高。
[Abstract]:Objective the macrovascular structural malformation of the heart is a kind of common fetal congenital developmental malformations. Due to the influence of many factors, antenatal routine two-dimensional echocardiography has some limitations in the diagnosis of fetal congenital heart disease. The purpose of this study was to evaluate the value of two-dimensional echocardiography combined with time-space correlation imaging (STIC) in the screening of fetal congenital heart disease. Methods from September 2011 to May 2013, 11036 pregnant women with fetal malformation were screened in our hospital. Two-dimensional ultrasound scanning and three-dimensional STIC imaging were performed with GE-Voluson E8 instrument. STIC volume database collection and offline analysis were carried out in some fetuses, and the scanning time of two-dimensional ultrasound and STIC heart was recorded. The results of postmortem or post-birth follow-up of fetuses with congenital heart disease were compared. Result 1. There was no significant difference between two-dimensional echocardiography and two-dimensional echocardiography combined with STIC in the diagnosis of 95 cases of fetal congenital heart disease (95.79% and 98.95%, respectively). two銆

本文编号：2496389