昆明地区妊娠期糖尿病发生的民族差异

发布时间：2019-06-19 01:05

【摘要】：目的调查生活在昆明地区不同少数民族妊娠期糖尿病(GDM)的发生率。方法对2004年1月至2013年12月10年期间在昆明3所医院接受75g口服葡萄糖耐量试验(OGTT)的18 195例单胎4个民族(包括汉族、回族、白族、彝族)孕妇进行前瞻性研究。采用1999年WHO制定的GDM诊断标准,比较不同民族组间GDM发生率。结果该地区研究期间GDM的总体发生率为12.4%。GDM发生率相比,回族显著高于汉族(17.5%vs.12.5%,P=0.026),而彝族显著低于汉族(6.4%vs.12.5%,P=0.003),白族发生率有升高的趋势(15.8%vs.12.5%,P=0.061)。Logistic回归显示,母亲年龄(OR=1.12,95%CI:1.10~1.14)、孕前BMI(OR=1.12,95%CI:1.06~1.17),OGTT时BMI(OR=1.45,95%CI:1.36~1.54)、一级亲属DM家族史(OR=1.96,95%CI:1.45~2.64)、白族(OR=1.63,95%CI:1.11~2.41)为GDM发生的独立危险因素。结论同一生活背景时不同民族间GDM的发生率存在差异,提示GDM的筛查中民族背景可以作为高危因素考虑。
[Abstract]:Objective to investigate the incidence of gestational diabetes mellitus (GDM) in different ethnic minorities living in Kunming. Methods from January 2004 to December 2013, 18 195 pregnant women from 4 nationalities (including Han, Hui, Bai and Yi) who underwent 75g oral glucose tolerance test (OGTT) in three hospitals in Kunming were studied prospectively. The GDM diagnostic criteria established by WHO in 1999 were used to compare the incidence of GDM among different ethnic groups. Results the overall incidence of GDM in Hui nationality was significantly higher than that in Han nationality (17.5% vs. 12.5%, P 鈮，

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