子宫富于细胞型平滑肌瘤150例临床分析
发布时间：2019-07-02 16:46
【摘要】：目的：分析子宫富于细胞型平滑肌瘤的临床特征、病理特点,探讨其生物学行为及临床结局,以达到对疾病更全面的认识,避免过度治疗或治疗不足。 方法：选取昆明医科大学第一附属医院妇科2013年1月～2013年12月间收治行手术治疗后病理诊断为子宫肌瘤的495例患者临床资料。富于细胞型平滑肌瘤150例纳入研究组,子宫平滑肌瘤100例纳入对照组。排出其他特殊类型的子宫肌瘤或子宫肉瘤245例。就其发病年龄、发病率、临床特征、病理特点、治疗方案及预后等方面进行回顾性分析研究。 结果：子宫富于细胞型平滑肌瘤发病年龄、临床特征、影像学检查、治疗方案、住院时间等与普通型平滑肌瘤相比,除痛经、贫血、B超提示部分高回声包块外均无显著性差异(P0.05)。术后随访130例,均存活,无一例复发、转移,预后良好。 结论：子宫富于细胞型平滑肌瘤是一种特殊类型的子宫肌瘤,病理组织学属良性肿瘤。因镜下细胞可异常丰富,甚至出现个别异型细胞,应与平滑肌肉瘤相鉴别。手术治疗可取得较好疗效。但相关文献报道,有晚期复发、转移的可能,甚至有复发后诊断为低度恶性平滑肌肉瘤的病例,因此术后诊断为子宫富于细胞型平滑肌瘤的患者应加强术后随访。
[Abstract]:Objective: to analyze the clinical and pathological characteristics of uterine cell-rich leiomyoma, and to explore its biological behavior and clinical outcome, so as to achieve a more comprehensive understanding of the disease and avoid excessive treatment or insufficient treatment. Methods: the clinical data of 495 patients with uterine myoma diagnosed pathologically from January 2013 to December 2013 in the first affiliated Hospital of Kunming Medical University were selected. 150 cases of cell-rich leiomyoma and 100 cases of uterine leiomyoma were included in the study group. 245 cases of other special types of uterine myoma or uterine sarcomas were excreted. The age of onset, incidence, clinical characteristics, pathological characteristics, treatment scheme and prognosis were analyzed and studied retrospectively. the age of onset, incidence, clinical characteristics, pathological characteristics, treatment scheme and prognosis were analyzed retrospectively. Results: there were no significant differences in age, clinical features, imaging examination, treatment scheme and hospitalization time between uterine cell-rich leiomyoma and common leiomyoma, except dysmenorrhea, anemia and B-ultrasound. 130 cases were followed up, all of them survived, no recurrence, metastasis and good prognosis. Conclusion: uterine cell-rich leiomyoma is a special type of uterine myoma, which belongs to benign tumor in pathology. Because of the abnormal abundance of cells and even the appearance of individual heterogeneic cells, it should be distinguished from leiomyosarcoma. Surgical treatment can achieve good results. However, it is reported that there is the possibility of late recurrence and metastasis, and even cases of low grade malignant leiomyosarcoma diagnosed after recurrence, so patients diagnosed as uterine cell-rich leiomyoma after operation should be followed up.
【学位授予单位】：昆明医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R737.33
本文编号：2509097
[Abstract]:Objective: to analyze the clinical and pathological characteristics of uterine cell-rich leiomyoma, and to explore its biological behavior and clinical outcome, so as to achieve a more comprehensive understanding of the disease and avoid excessive treatment or insufficient treatment. Methods: the clinical data of 495 patients with uterine myoma diagnosed pathologically from January 2013 to December 2013 in the first affiliated Hospital of Kunming Medical University were selected. 150 cases of cell-rich leiomyoma and 100 cases of uterine leiomyoma were included in the study group. 245 cases of other special types of uterine myoma or uterine sarcomas were excreted. The age of onset, incidence, clinical characteristics, pathological characteristics, treatment scheme and prognosis were analyzed and studied retrospectively. the age of onset, incidence, clinical characteristics, pathological characteristics, treatment scheme and prognosis were analyzed retrospectively. Results: there were no significant differences in age, clinical features, imaging examination, treatment scheme and hospitalization time between uterine cell-rich leiomyoma and common leiomyoma, except dysmenorrhea, anemia and B-ultrasound. 130 cases were followed up, all of them survived, no recurrence, metastasis and good prognosis. Conclusion: uterine cell-rich leiomyoma is a special type of uterine myoma, which belongs to benign tumor in pathology. Because of the abnormal abundance of cells and even the appearance of individual heterogeneic cells, it should be distinguished from leiomyosarcoma. Surgical treatment can achieve good results. However, it is reported that there is the possibility of late recurrence and metastasis, and even cases of low grade malignant leiomyosarcoma diagnosed after recurrence, so patients diagnosed as uterine cell-rich leiomyoma after operation should be followed up.
【学位授予单位】：昆明医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R737.33
【参考文献】
相关期刊论文 前2条
1 石一复，谢幸，赵承洛，吕卫国;子宫交界性平滑肌瘤的病理诊断及临床特征[J];中华妇产科杂志;1994年04期
2 狄文;吕煊;;特殊类型子宫肌瘤分型及其诊治要点[J];中国实用妇科与产科杂志;2012年12期
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