治疗前患者外周血PLR与宫颈鳞状细胞癌预后的关系

发布时间：2019-07-11 06:21

【摘要】：目的探讨治疗前外周血血小板与淋巴细胞比(PLR)和宫颈鳞状细胞癌患者预后的关系。方法回顾性分析143例宫颈鳞状细胞癌患者的临床病理资料,根据统计学方法选取PLR截断值,将患者根据截断值分组,分析PLR与宫颈鳞状细胞癌患者生存、复发情况的关系以及与临床病理参数的关系。结果选取PLR=125作为截断值。PLR≥125者及PLR125者5年生存率分别为54.5%、81.6%,复发率分别为50.0%、22.4%,两组比较,P均0.05。PLR与宫颈鳞状细胞癌患者年龄、FIGO分期、术前化疗、病灶直径、血小板计数有关,患者预后与宫颈鳞状细胞癌FIGO分期、病灶直径、术前有无化疗、PLR、血小板计数有关。Cox回归分析显示,PLR、FIGO分期、血小板计数、病灶直径、术前是否有化疗是影响是宫颈鳞癌患者术后生存和复发的独立危险因素。结论治疗前外周血PLR与宫颈鳞状细胞癌患者预后有关,其可作为宫颈鳞状细胞癌患者病情评估的指标。
[Abstract]:Objective to investigate the relationship between peripheral blood platelet / lymphocyte ratio (PLR) and prognosis in patients with cervical squamous cell carcinoma before treatment. Methods the clinicopathological data of 143 patients with cervical squamous cell carcinoma were analyzed retrospectively. according to the statistical method, the cut-off values of PLR were selected and divided into groups according to the cut-off values. The relationship between PLR and survival and recurrence of cervical squamous cell carcinoma was analyzed, as well as the relationship between PLR and clinicopathological parameters. Results the 5-year survival rate of PLR=125 鈮，

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